EndoCleave High Quality (HQ) is a recombinant endonuclease, expressed in E. coli, that efficiently digests DNA and RNA. EndoCleave HQ is primarily designed for process development (PD) and purification scouting to remove nucleic acids (from host cells and plasmids) during the pre-clinical stages of viral vector and gene therapy workflows.
Functioning as the 'Technical Twin' to our GMP Grade enzyme, EndoCleave HQ offers the identical host, process, and purity (>99%) at a cost-effective price point.
Transition to GMP Grade compliance with confidence
When your project advances to clinical phases, you can transition to EndoCleave GMP Grade with complete confidence. This version with extended impurity testing and provides the extensive quality documentation to help you meet regulatory compliance required for large-scale therapeutic manufacturing.
