Product launch: EndoCleave for viral vector, vaccine and biopharma manufacturing
Maximize viral vector yields with EndoCleave endonucleases - High Quality and GMP Grade
Efficient nucleic acid digestion is critical for the integrity and yield of viral vector manufacturing. The EndoCleave portfolio offers high-performance recombinant endonucleases expressed in E. coli, engineered specifically to degrade all forms of DNA and RNA. By rigorously eliminating host cell impurities and residual plasmids, EndoCleave provides the purity and safety profile essential for advanced biopharmaceutical applications.
We offer EndoCleave in two quality grades (High Quality and GMP Grade) to optimize your workflow and manage costs across the product lifecycle. Both versions utilize an identical host expression system and a high-purity, animal origin-free (AOF) formulation.
Technical twins
- Identical formulation & purity (>99%)
- Unified E.coli expression system from bench to clinic
- AOF and AB-free
- Certificate of Equivalence available
Strategic risk mitigation
Starting with EndoCleave High Quality (HQ) and transitioning to GMP Grade provides critical advantages for clinical readiness:
Request your EndoCleave endonuclease sample here
EndoCleave High Quality (HQ)
A high-purity (>99%), cost-effective 'Technical Twin' thoughtfully engineered to harmonize with our GMP Grade enzyme. Sharing the same E. coli host and manufacturing process, EndoCleave HQ helps to minimize the possibility of technical variations as you scale up. This close alignment offers assurance that the nucleic acid digestion processes developed during initial purification work and pre-clinical development will remain consistent and easily reproducible when you transition toward commercial manufacturing.
Order information and specifications for
EndoCleave High Quality (HQ)
EndoCleave GMP Grade
A high-purity (>99%), GMP Grade product specifically engineered to maintain the rigorous safety profile and regulatory compliance essential for large-scale viral vector and therapeutic manufacturing.
Manufactured under 21 CFR 820 and ISO 13485:2016 standards with validated cleaning processes, this product supports commercial-scale bioprocessing through an extensive quality documentation package and extended testing for impurities, such as heavy metals, proteases, and host cell proteins.
Order information and specifications for
EndoCleave GMP Grade
Regulatory disclaimer, warranty limitations and legal notes are listed on the respective product page.
