For further processing into medical devices, IVD and pharmaceutical products only. Others EndoCleave rec. GMP Grade AOF EndoCleave, rec., GMP Grade, AOF 102 1584029687338397 Warranty LimitationIt is the sole responsibility of the customer to determine the suitability of all raw materials, products and components in order to ensure that the final end-use product is safe for its end use; performs or functions as intended; and complies with all applicable legal and regulatory requirements. Roche makes no representations or warranties of any kind regarding the Product, express or implied, other than those expressly set forth in the terms and conditions of sale (if any), and disclaims all implied or statutory warranties including warranty of merchantability and fitness for a particular purpose. PID00000909 from Serratia marcescens, recombinant, expressed in E.coli, solution 10 360 364 103 10360364103 EndoCleave rec., GMP Grade, AOF, 500 KU EndoCleave rec., GMP Grade, AOF, 500 KU Reagents, kits 500KU Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "EndoCleave, rec., GMP Grade, AOF". Unit of measure is "mL". 10 360 500 103 10360500103 EndoCleave rec., GMP Grade, AOF, 100 KU EndoCleave rec., GMP Grade, AOF, 100 KU Reagents, kits 100KU Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "EndoCleave, rec., GMP Grade, AOF". Unit of measure is "mL". 10 360 321 103 10360321103 EndoCleave rec., GMP Grade, AOF, 5000 KU EndoCleave rec., GMP Grade, AOF, 5000 KU Reagents, kits 5000KU Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "EndoCleave, rec., GMP Grade, AOF". Unit of measure is "mL". 9025-65-4 en EC 3.1.30.2. en Designed for use in the purification of viral vectors, oncolytic viruses and viral vaccines to digest the nucleic acids in the harvest . en Appearance: clear colourless solution Volume activity: 250 - 350 kU/ml Purity (SDS-PAGE), Purity of bands ≥ 99 %: corresponds Proteases not detectable (50 µg protein with resorufin marked casein;15 min; 37°C): corresponds Endotoxins: < 5 EU/ml Host cell protein ≤ 50 ppm: corresponds Bioburden: < 5 CFU/ml Heavy metals ICP-MS (sum Ni, Co, V) ≤ 10 ppm: corresponds Stability: At -25 °C to -15 °C within specification range for 18 months. en EndoCleave digests both DNA and RNA and can be used in applications that need nucleic acid digestion to - prevent clumping of cells - remove DNA/RNA in protein applications - remove DNA/RNA in viral vector purification en

Unlock excellence in viral vector production with EndoCleave

EndoCleave is a recombinant endonuclease, expressed in E. coli, that digests DNA and RNA. EndoCleave is primarily designed for use in the digestion of nucleic acids (from host cells and plasmids) during viral vector production and purification for gene therapy.

EndoCleave is developed in a fit-for-purpose format and provides the performance, quality, and scale you need for your viral vector production and any other biopharma applications where nucleic acid digestion is needed.

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