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{
"ProductData": {
"RelatedLinks": "",
"RegulatoryDisclaimer1": "For further processing only.",
"RegulatoryDisclaimer2": "",
"StainLocalization": [
""
],
"ProductType": "Others",
"DisclaimerGroup2": null,
"ProductNameGlobal": "Pepstatin lyophilizate",
"DisclaimerGroup1": "Non-IVD",
"ControlTissue": [
""
],
"BrandName": "Pepstatin",
"LicenseDisclaimers": [
],
"Isotypes": "",
"RegulatoryDisclaimer3": "",
"ID": "3.2.7.1.28.1",
"ProductNameAddition": "from Streptomyces species, lyophilizate",
"Species": [
""
],
"Clone": ""
},
"ProductImageDetails": {
"ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png",
"ImageType": "Image main"
},
"Product2Taxomony": {
"Product2TaxomonyReferences": [
{
"StructureSystemIdentifier": "OWP_Product_Solutions",
"StructureSystemName": "OWP Product Solutions",
"NodeName": "CustomBiotech",
"NodeID": "520"
},
{
"StructureSystemIdentifier": "OWP_Product_Types",
"StructureSystemName": "OWP Product Types",
"NodeName": "Raw Materials->Protease inhibitors",
"NodeID": "70-043-00"
},
{
"StructureSystemIdentifier": "OWP_Organization",
"StructureSystemName": "OWP Organization",
"NodeName": "Roche Diagnostics Solution (RDS)->Customer Areas->Core lab->CustomBiotech and LifeScience",
"NodeID": "01-01-01-07-00"
},
{
"StructureSystemIdentifier": "Product_Solutions",
"StructureSystemName": "Product Solutions",
"NodeName": "CustomBiotech",
"NodeID": "520"
}
]
},
"Product2Materials": {
"P2MaterialReferences": [
{
"MaterialNum": "10253294103",
"MaterialDescription": "Pepstatin from Streptomyces species",
"RegisteredProductName": "Pepstatin",
"GTIN": "",
"ProductCategoryText": "Reagents, kits",
"OldMaterialNumber": "",
"PackSizePIM360": "custom fill",
"PackSizeDescPIM360": "",
"MaterialAnnotation": "CustomBiotech product. Please contact your local representative.",
"ReadyForUse": "",
"OrderInformation": "Will be supplied as \"Pepstatin from Sreptomyces species\". Unit of measure is \"g\"."
}
]
},
"Product2Products": {
"Product2ProductReference": [
]
},
"ProductSpec": [
{
"ProductSpecVariant": {
"Chapters": [
{
"Language": "en",
"Value": "Pepstatin is highly purified according to HPLC analysis.",
"Name": "Quality Control"
},
{
"Language": "en",
"Value": "Pepstatin is a highly efficient inhibitor for many aspartic and acid proteases. It is a hexa-peptide containing the unusual amino acid statine (Sta, (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid), having the sequence Iva-Val-Val-Sta-Ala-Sta. Pepstatin is known for its ability to inhibit pepsin in a picomolar concentration. The product is soluble in methanol and ethanol, but insoluble in water.",
"Name": "Product Description"
},
{
"Language": "en",
"Value": "Pepstatin is a protease inhibitor.",
"Name": "Positioning"
},
{
"Language": "en",
"Value": "Use Pepstatin to inhibit potently the HIV protease and other aspartic proteases such as pepsin, renin, cathepsin D, chymosin, and many microbial acid proteases.",
"Name": "Applications"
},
{
"Language": "en",
"Value": "Will be supplied as \"Pepstatin from Sreptomyces species\". Unit of measure is \"g\".",
"Name": "CB - Order Information"
},
{
"Language": "en",
"Value": "Appearance: White powder Solubility: Clear to slightly opalescent, colorless solution in methanol (c=1 mg/mL) Clear, colorless solution in methanol (c=20 mg/mL) Clear to slightly opalescent, colorless solution in ethanol (overnight) Performance of inhibition of pepsin: With 0.01 mL sample: ≥85% With 0.1 mL sample: ≥100% Values are taken from supplier certificate: Melting range: +232 to +237°C Purity (HPLC): ≥98 area% Stability: At +2 to +8°C within specification range for 24 months.",
"Name": "Specification"
},
{
"Language": "en",
"Value": "CAS Number: 151662-36-1 Formula: C34H63N5O9 Molecular weight: 685.9 D Pepstatin is soluble in methanol (1 mg/mL and 20 mg/mL as well) and ethanol (1 mg/ml) if you allowed to sit overnight, and to 300 μg/ml in 6 N acetic acid. Stable at least 1 week at +2 to +8°C or 1 month if stored in aliquots at -15 to -25°C.",
"Name": "Properties"
}
]
}
}
]
}