{
"ProductData": {
"ID": "3.2.7.1.28.1",
"ProductType": "Others",
"BrandName": "Pepstatin",
"ProductNameAddition": "from
Streptomyces species, lyophilizate",
"RegulatoryDisclaimer1": "For further processing only.",
"DisclaimerGroup1": "",
"RegulatoryDisclaimer2": null,
"DisclaimerGroup2": null,
"RegulatoryDisclaimer3": null,
"SampleType": [
],
"LicenseDisclaimers": [
],
"RelatedLinks": "",
"Clone": "",
"ControlTissue": [
""
],
"ISOtypes": "",
"Species": [
""
],
"StainLocalization": [
""
],
"ProductNameGlobal": "Pepstatin lyophilizate"
},
"ProductImageDetails": {
"ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png",
"ImageType": "Image main"
},
"Product2Taxonomy": {
"Product2TaxonomyReferences": [
{
"StructureSystemIdentifier": "OWP_Product_Types",
"StructureSystemName": "Product Types",
"StructureNodeStatus": "valid",
"NodeName": "Protease inhibitors",
"NodeID": "70-043-00"
},
{
"StructureSystemIdentifier": "OWP_Organization",
"StructureSystemName": "Organization",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech and LifeScience",
"NodeID": "01-01-01-07-00"
},
{
"StructureSystemIdentifier": "Product_Solutions",
"StructureSystemName": "Product Solutions",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech",
"NodeID": "520"
},
{
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"StructureSystemName": "Lab Types",
"StructureNodeStatus": "invalid",
"NodeName": "",
"NodeID": "180-00"
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{
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"StructureSystemName": "Applications",
"StructureNodeStatus": "invalid",
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"NodeID": "99-00-00"
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{
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"StructureSystemName": "Techniques",
"StructureNodeStatus": "invalid",
"NodeName": "",
"NodeID": "999-00"
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{
"StructureSystemIdentifier": "Disease_Areas",
"StructureSystemName": "Disease Areas",
"StructureNodeStatus": "invalid",
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{
"StructureSystemIdentifier": "Pathogens",
"StructureSystemName": "Pathogens",
"StructureNodeStatus": "invalid",
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"StructureSystemName": "Product Families",
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{
"StructureSystemIdentifier": "Health_Topics",
"StructureSystemName": "Health Topics",
"StructureNodeStatus": "invalid",
"NodeName": "",
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]
},
"Product2Materials": {
"P2MaterialReferences": [
{
"MaterialNum": "10253294103",
"MaterialDescription": "Pepstatin from Streptomyces species",
"RegisteredProductName": "Pepstatin",
"GTIN": "",
"ProductCategoryText": "Reagents, kits",
"OldMaterialNumber": "",
"PackSizePIM360": "custom fill",
"PackSizeDescPIM360": "Not Available",
"MaterialAnnotation": "CustomBiotech product. Please contact your
local representative.",
"ReadyForUse": "",
"OrderInformation": "Will be supplied as \"Pepstatin from Sreptomyces species\". Unit of measure is \"g\"."
}
]
},
"Product2Products": {
"Product2ProductReference": [
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},
"ProductSpec": [
{
"ProductSpecVariant": {
"Chapters": [
{
"Language": "en",
"Value": "Pepstatin is highly purified according to HPLC analysis.",
"Country": "XG",
"Code": "Quality Control",
"Name": "Quality Control"
},
{
"Language": "en",
"Value": "Pepstatin is a highly efficient inhibitor for many aspartic and acid proteases. It is a hexa-peptide containing the unusual amino acid statine (Sta, (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid), having the sequence Iva-Val-Val-Sta-Ala-Sta. Pepstatin is known for its ability to inhibit pepsin in a picomolar concentration. The product is soluble in methanol and ethanol, but insoluble in water.",
"Country": "XG",
"Code": "Product Description",
"Name": "Product Description"
},
{
"Language": "en",
"Value": "Pepstatin is a protease inhibitor.",
"Country": "XG",
"Code": "Positioning",
"Name": "Positioning"
},
{
"Language": "en",
"Value": "Use Pepstatin to inhibit potently the HIV protease and other aspartic proteases such as pepsin, renin, cathepsin D, chymosin, and many microbial acid proteases.",
"Country": "XG",
"Code": "Applications",
"Name": "Applications"
},
{
"Language": "en",
"Value": "Will be supplied as \"Pepstatin from Sreptomyces species\". Unit of measure is \"g\".",
"Country": "XG",
"Code": "CB - Order Information",
"Name": "CB - Order Information"
},
{
"Language": "en",
"Value": "
Appearance: White powder
Solubility:
Clear to slightly opalescent, colorless solution in methanol (c=1 mg/mL)
Clear, colorless solution in methanol (c=20 mg/mL)
Clear to slightly opalescent, colorless solution in ethanol (overnight)
Performance of inhibition of pepsin:
With 0.01 mL sample: ≥85%
With 0.1 mL sample: ≥100%
Values are taken from supplier certificate:
Melting range: +232 to +237°C
Purity (HPLC): ≥98 area%
Stability: At +2 to +8°C within specification range for 24 months.",
"Country": "XG",
"Code": "Specification",
"Name": "Specification"
},
{
"Language": "en",
"Value": "
CAS Number: 151662-36-1
Formula: C
34H
63N
5O
9Molecular weight: 685.9 D
Pepstatin is soluble in methanol (1 mg/mL and 20 mg/mL as well) and ethanol (1 mg/ml) if you allowed to sit overnight, and to 300 μg/ml in 6 N acetic acid. Stable at least 1 week at +2 to +8°C or 1 month if stored in aliquots at -15 to -25°C.",
"Country": "XG",
"Code": "Properties",
"Name": "Properties"
}
]
}
}
]
}