{ "ProductData": { "ID": "3.1.1.4.9.3", "ProductType": "Others", "BrandName": "L-Lactate Dehydrogenase (L-LDH), chemically modified", "ProductNameAddition": "from pig heart, lyophilizate", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": "", "DisclaimerGroup2": null, "RegulatoryDisclaimer3": "", "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "L-Lactate Dehydrogenase L-LDH chemically modified" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Enzymes", "NodeID": "02-0014" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "StructureNodeStatus": "valid", "NodeName": "Dehydrogenases", "NodeID": "70-014-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Clinical Chemistry Raw Materials", "NodeID": "02-0011" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "valid", "NodeName": "Enzyme Testing", "NodeID": "06-00-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "180-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "11866117103", "MaterialDescription": "Lactate Dehydrogenase (LDH)", "RegisteredProductName": "L-Lactate Dehydrogenase (L-LDH), chemically modified", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Lactate Dehydrogenase (LDH)\". Unit of measure is \"MU\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Use L-Lactate Dehydrogenase (L-LDH), chemically modified, in a variety of diagnostic tests for the removal of pyruvate in determinations working with NADH (i.e., triglycerides, lipase, aldolase, aminotransferases, glutamate dehydrogenase). The chemical modification generates an increased liquid stability of the enzyme.", "Country": "XG", "Code": "Applications", "Name": "Applications" }, { "Language": "en", "Value": "Will be supplied as \"Lactate Dehydrogenase (LDH)\". Unit of measure is \"MU\".", "Country": "XG", "Code": "CB - Order Information", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Dehydrogenase that catalyzes the interconversion of L(+)-lactate to pyruvate.", "Country": "XG", "Code": "Positioning", "Name": "Positioning" }, { "Language": "en", "Value": "Appearance: White lyophilizate
Solubility: Clear, colorless solution in water (c=10 mg/mL)
pH value: 7.1-8.1
Activity (+25°C, pyruvate): ≥25 U/mg lyophilizate
Specific activity: ≥150 U/mg protein
Protein (BCA): 0.15-0.25 mg/mg lyophilizate
Contaminants (expressed as percentage of Lactate Dehydrogenase activity):
Aspartate aminotransferase (AST/GOT): ≤0.005
Unspecificity of Lactate dehydrogenase: ≤0.05
Alanine aminotransferase (ALT/GPT): ≤0.01
Unspecificity of Lactate dehydrogenase: ≤0.05
''NADH-Oxidase'': ≤0.001
SVD free: Corresponds to specification
pH 5.5 treatment (30 minutes): Corresponds to specification
Stability in CAPSO (pH 9.4, at +60°C for 1 hour): ≥50%
Stability: At +2 to +8°C within specification range for 12 months.", "Country": "XG", "Code": "Specification", "Name": "Specification" }, { "Language": "en", "Value": "CAS Number: 9001-60-9", "Country": "XG", "Code": "Properties", "Name": "Properties" } ] } } ] }