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{
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"RegulatoryDisclaimer1": "For use in quality control / manufacturing process only.",
"RegulatoryDisclaimer2": "",
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"ProductNameGlobal": "Acetate V2 Bio",
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"BrandName": "Acetate V2 Bio",
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"ID": "3.8.10.2.4.20",
"ProductNameAddition": "Test kit for the Cedex Bio Analyzer",
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"ProductSpec": {
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"Language": "English",
"Value": "Store the reagent at +2 to +8°C.",
"Name": "Storage Conditions (Product)"
},
{
"Language": "English",
"Value": "Keep at +2 to +10°C for on board use. On-board stability: After first use on the instrument, the reagent is stable for up to 4 weeks.",
"Name": "Storage Conditions (Working Solution)"
},
{
"Language": "English",
"Value": "Applications AC2B (031), AC2D (O32)
AC2B is the standard protocol for acetate determination. If the acetate concentration of a sample is expected to be higher than 2.3 g/L (38.9 mmol/L), then protocol AC2D should be used (same protocol with preset 1:10 sample predilution). Results higher than the valid measuring range will be flagged and a rerun with an automatic 1:10 predilution will be recommended by the software.
Cedex Bio test definition: Measuring mode Absorbance Abs. calculation mode Endpoint Reaction direction Increase Wavelength A/B 340/409 nm Calc. first/last 23/40 Unit mmol/L Reaction mode R1-S-SR
Calibration: Calibrator Calibrator D Bio (CALD, 794) Calibration mode Linear regression Calibration interval 56 days, and if recalibration is required due to QC results
Quality control: Controls Control D Level 1 Bio (COND1, 307) Control D Level 2 Bio (COND2, 308) Control D Level 3 Bio (COND3, 309) Use the recommended control material. Other suitable control material can be used in addition. Control intervals and acceptance limits should be adapted to each laboratory's individual requirements. If values do not fall within the defined limits, corrective measures and recalibration are required
",
"Name": "Protocols - Help Corner"
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{
"Language": "English",
"Value": "This product is intended for quantitative determination of acetate in aqueous solutions using the Cedex Bio Analyzer.",
"Name": "Product Description"
},
{
"Language": "English",
"Value": "Acetic acid (acetate) is converted to acetyl-CoA by acetate kinase (AK) and phosphotransacetylase (PTA). Acetyl-CoA reacts with oxaloacetate in the presence of citrate synthase (CS) to produce citrate. The oxaloacetate for this reaction is generated by conversion of malate by L-malate dehydrogenase (MDH) with the reduction of NAD to NADH. The formation of NADH is measured by increase in absorbance at 340 nm, which relates to the concentration of acetic acid.
",
"Name": "Content"
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{
"Language": "English",
"Value": "Measuring Range Acetate concentration can be determined in following range:
AC2B: 15 - 2300 mg/L (0.25 - 38.8 mmol/L)
AC2D: 1.5 - 23 g/L (2.5 - 388 mmol/L), up to 230 g/L (3.88 mol/L) with automatic predilution
Conversion Factors Conversion factors for acetate concentration:
1 mmol/L = 59.05 mg/L
1 g/L = 16.93 mmol/L
Traceability This method has been standardized against an independent photometric ezymatic assay.
Precision Representative performance data on Cedex Bio Analyzers are shown. Results obtained in individual laboratories may differ. Precision was determined in samples of three concentration levels. Coefficients of variation (CV) were calculate in-run precision (n=21) and inter-run precision (on 10 days).
Level 1
Level 2
Level 3
Mean
2.79 mmol/L (165 mg/L)
17.83 mmol/L (1053 mg/L)
28.41 mmol/L (1678 mg/L)
CV in-run
1.04 %
3.64 %
5.58 %
CV inter-run
3.67 %
2.73 %
6.34 %
",
"Name": "Background Information - Help Corner"
},
{
"Language": "English",
"Value": "Acetate is an important metabolyte in microbial fermentation. Accumulation of acetate can suppress culture growth and product formation. For monitoring in a culture process, acetate can be determined on a Cedex Bio or Cedex Bio HT Analyzer with high reliability and convenience.",
"Name": "Applications"
},
{
"Language": "English",
"Value": "Method: Enzymatic photometric assay using phosphorylation by acetate kinase. Recovery: ±15%",
"Name": "Specification"
}
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"BrandName": "Control D Level 1 Bio",
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For measurement of acute pancreatitis (pancreatic α-amylase) in human serum and urine selective blocking of salivary α-amylase isoenzyme is achieved in the presence of the pancreatic h-α-amylase.Qualified for thecobas platforms.
Product Description
For measurement of acute pancreatitis (pancreatic α-amylase) in human serum and urine selective blocking of salivary α-amylase isoenzyme is achieved in the presence of the pancreatic h-α-amylase.Qualified for thecobas platforms.
Ordering
Name
PackSizePIM360
Description
11543601103
custom fill
MAKM-Tu66C7-IgG(BR)SQ
Notes
Will be supplied as "MAK<H-S-Amy>M-Tu66C7-IgG(BR)SQ". Unit of measure is "g active ingredient".
