Ig Fab Bio
Test kit for the Cedex Bio Analyzer
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Unit of measure is "piece".
Ig Fab Bio material number and pack size: Material Number Pack Size 08881332001 4 x 50 tests - Kit for determination of human immunoglobulin Fab fragments. This product is intended for quantitative determination of human immunoglobulin Fab fragments in aqueous solutions using the Cedex Bio Analyzer.
- In oncology, immunoglobulins (Ig) are used for therapeutic treatment. There is a need in the pharmaceutical development and manufacturing to determine the antibody concentrations. Complete IgG antibodies can be determined using the 'IgG Bio' test, detecting the highly conserved Fc part of the molecules. Nevertheless, a rising number of artificially designed Ig products consists of the target binding Fab part only, missing the Fc region. The 'Ig Fab Bio' test detects a constant region of the Kappa Light Chain in the Ig Fab fragment. Therefore, this test is suited also for the determination of truncated Ig fragments.
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Method: Immunoturbidimetric;
Recovery: ± 15%