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For further processing into medical devices, IVD and pharmaceutical products only. Others UTP 100 mM pH 7.4 GMP Grade AOF UTP, GMP Grade, AOF 102 1584029687338397 Warranty LimitationIt is the sole responsibility of the customer to determine the suitability of all raw materials, products and components in order to ensure that the final end-use product is safe for its end use; performs or functions as intended; and complies with all applicable legal and regulatory requirements. Roche makes no representations or warranties of any kind regarding the Product, express or implied, other than those expressly set forth in the terms and conditions of sale (if any), and disclaims all implied or statutory warranties including warranty of merchantability and fitness for a particular purpose. PID00000728 100 mM, pH 7.4 09 962 654 103 9 962 654 103 09962654103 9962654103 09962654103 UTP, 100 mM pH 7.4, GMP Grade AOF UTP, 100 mM pH 7.4, GMP Grade AOF Reagents, kits 100 mL Not Available CustomBiotech product. Please contact your local representative. Unit of measure is "mL". Will be supplied as "UTP, GMP Grade, AOF, 100 mM, pH 7.4". Minimum Order: 4000 mL 63-39-8 (free acid) en Appearance: Clear, colorless solutionpH value: 7.3-7.5 (25 °C ± 1 °C)UTP (A260; pH 7.0 ε = 15.0 [L x mmol-1 x cm-1]): 97-103 mmol/LUTP (HPLC): ≥ 98.5 area%UDP (HPLC): ≤ 1.5 area%UMP (HPLC): ≤ 0.5 area%Sum from UTP + UDP + UMP (HPLC): ≥ 99.5 area%Heavy metals (sum from V, Ni with ICP-MS): ≤ 10 ppmProteases (recovery Aldolase ≥ 80%): Corresponds to specificationBioburden (TAMC): ≤ 3 CFU/mlBioburden (TYMC): ≤ 2 CFU/mlEndotoxins: ≤ 2 EU/mlDNases/RNases: NegativeNicking activity: NegativeFunctional transcription assay: Corresponds to specificationIdentity HPLC-MS: Corresponds to specificationStability: At -15 to -25°C within specification range for 18 months from date of manufacture. en This Uridine Triphosphate (UTP) solution is engineered for demanding in vitro transcription (IVT) applications where quality, compliance, and process flexibility are critical. We manufacture this UTP under our stringent GMP Grade guidelines to support your regulatory requirements; the manufacturing process, including the final filling step, is validated, and every batch undergoes comprehensive QC-release testing. Our production utilizes a sustainable, non-chemical enzymatic process that avoids the heavy metal catalysts often used in chemical synthesis, and the product is certified completely animal-origin free (AOF). To ensure product integrity and a stable pH during shipment on dry ice, it is supplied in sealed, CO2-proof bottles. en NTPs are the critical starting materials of in vitro mRNA synthesis for therapeutics or vaccines. en Together with CTP, ATP, GTP and/or modified UTP, UTP is part of the ribonucleotide mix needed to synthesize mRNA in the presence of a RNA polymerase. en