{
"ProductData": {
"ID": "3.1.5.1.1.2",
"ProductType": "Others",
"BrandName": "Urease",
"ProductNameAddition": "from jack bean, lyophilizate",
"RegulatoryDisclaimer1": "For further processing only.",
"DisclaimerGroup1": "",
"RegulatoryDisclaimer2": null,
"DisclaimerGroup2": null,
"RegulatoryDisclaimer3": null,
"SampleType": [
],
"LicenseDisclaimers": [
],
"RelatedLinks": "",
"Clone": "",
"ControlTissue": [
""
],
"ISOtypes": "",
"Species": [
""
],
"StainLocalization": [
""
],
"ProductNameGlobal": "Urease"
},
"ProductImageDetails": {
"ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png",
"ImageType": "Image main"
},
"Product2Taxonomy": {
"Product2TaxonomyReferences": [
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"StructureNodeStatus": "valid",
"NodeName": "Enzymes",
"NodeID": "02-0014"
},
{
"StructureSystemIdentifier": "OWP_Product_Types",
"StructureSystemName": "Product Types",
"StructureNodeStatus": "valid",
"NodeName": "Hydrolases",
"NodeID": "70-023-00"
},
{
"StructureSystemIdentifier": "OWP_Organization",
"StructureSystemName": "Organization",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech and LifeScience",
"NodeID": "01-01-01-07-00"
},
{
"StructureSystemIdentifier": "Product_Solutions",
"StructureSystemName": "Product Solutions",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech",
"NodeID": "520"
},
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"StructureNodeStatus": "invalid",
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"StructureSystemName": "Applications",
"StructureNodeStatus": "invalid",
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"NodeName": "",
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"StructureSystemIdentifier": "Pathogens",
"StructureSystemName": "Pathogens",
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"StructureSystemIdentifier": "Health_Topics",
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"StructureNodeStatus": "invalid",
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},
"Product2Materials": {
"P2MaterialReferences": [
{
"MaterialNum": "11759132103",
"MaterialDescription": "Urease,Lyo.,SQ",
"RegisteredProductName": "Urease",
"GTIN": "",
"ProductCategoryText": "Reagents, kits",
"OldMaterialNumber": "",
"PackSizePIM360": "custom fill",
"PackSizeDescPIM360": "Not Available",
"MaterialAnnotation": "CustomBiotech product. Please contact your
local representative.",
"ReadyForUse": "",
"OrderInformation": "Will be supplied as \"Urease, Lyo., SQ\". Unit of measure is \"MU\"."
}
]
},
"Product2Products": {
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},
"ProductSpec": [
{
"ProductSpecVariant": {
"Chapters": [
{
"Language": "en",
"Value": "Use Urease in diagnostic tests for the determination of urea in combination with Glutamate Dehydrogenase.",
"Country": "XG",
"Code": "Applications",
"Name": "Applications"
},
{
"Language": "en",
"Value": "Will be supplied as \"Urease, Lyo., SQ\". Unit of measure is \"MU\".",
"Country": "XG",
"Code": "CB - Order Information",
"Name": "CB - Order Information"
},
{
"Language": "en",
"Value": "Hydrolase that catalyzes the breakdown of urea in carbon dioxide and ammonia.",
"Country": "XG",
"Code": "Positioning",
"Name": "Positioning"
},
{
"Language": "en",
"Value": "
Appearance: Almost white lyophilizate
Solubility: Clear, colorless solution in water (c=20 mg/mL)
pH value (c=20 mg/mL in water): 6.0-7.0
Activity (+25° C, urea): ≥45 U/mg lyophilizate
Specific activity: ≥600 U/mg protein
Protein (Biuret): ≤0.15 mg/mg lyophilizate
Contaminants (expressed as percentage of Urease activity):
L-Arginase: ≤0.002
NH4: ≤1.5 μg/KU
Stability: At +2 to +8°C within specification range for 12 months. Store dry.",
"Country": "XG",
"Code": "Specification",
"Name": "Specification"
},
{
"Language": "en",
"Value": "
Nomenclature: Urea amidohydrolase
CAS Number: 9002-13-5
Molecular weight: 480 kD
Isoelectric point: 5.0-5.1
Michaelis constant (Phosphate buffer, pH 7.0; +25°C):
Urea: 1.05 x 10
-2 mol/L
Inhibitors: Na
+, K
+, NH
4+; suramin and thiourea are competitive inhibitors.
Activators: P
ipH optimum: 7.5 (see figure)
Temperature dependence: See figure
pH stability: 6.0-9.5 (see figure)
Thermal stability: Up to +70° C (see figure)
Specificity: Urease is specific for urea.",
"Country": "XG",
"Code": "Properties",
"Name": "Properties"
}
]
}
}
]
}