{ "ProductData": { "ID": "3.2.17.2.67.0", "ProductType": "Others", "BrandName": "UDP-N-Acetylgalactosamine", "ProductNameAddition": "sodium salt, lyophilizate", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": null, "DisclaimerGroup2": null, "RegulatoryDisclaimer3": null, "SampleType": [ ], "LicenseDisclaimers": [ { "Order": "78", "Identifier": "1403506419168", "LongText": "The sale of the Product does not exhaust or grant any rights in third party patents including patents of companies of the F. Hoffmann - La Roche AG group of companies, in particular, for the use of modified antibodies obtained by using the product." } ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "UDP-N-Acetylgalactosamine" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "In vitro Glycoengineering", "NodeID": "02-0052" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "StructureNodeStatus": "valid", "NodeName": "Activated sugars", "NodeID": "70-001-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "180-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "06369855103", "MaterialDescription": "UDP-N-Acetylgalactosamine, Disodium", "RegisteredProductName": "UDP-N-Acetylgalactosamine", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Unit of measure is \"gram\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Unit of measure is \"gram\".", "Country": "XG", "Code": "CB - Order Information", "Name": "CB - Order Information" }, { "Language": "en", "Value": "UDP-N-Acetylgalactosamine is an activated sugar, and can be used for in vitro glycoengineering of glycoproteins, e.g. therapeutic proteins.", "Country": "XG", "Code": "Positioning", "Name": "Positioning" }, { "Language": "en", "Value": "UDP-N-Acetylgalactosamine is a disodium salt, provided as a white, lyophilized substance.", "Country": "XG", "Code": "Product Description", "Name": "Product Description" }, { "Language": "en", "Value": "Benefits of using in vitro glycoengineering to modify glycosylation of therapeutic proteins:

• Time- and cost-saving generation of glycan variants to develop improved drugs
• Optimized glycosylation without compromising other CQAs or product yield
• Improved lot-to-lot consistency to reduce risk of product quality variation and resulting delays
• Generation of glycoprofiles which may not otherwise be generated
• Streamlined analytics in comparability studies

", "Country": "XG", "Code": "Benefits", "Name": "Benefits" }, { "Language": "en", "Value": "UDP-N-Acetylgalactosamine can be used for glycosylation of target molecules with a suitable enzyme.", "Country": "XG", "Code": "Applications", "Name": "Applications" }, { "Language": "en", "Value": "Appearance: White powder
Solution (c = 100 mg/mL water): Clear, colorless
Identity (¹H-NMR): spectrum conforms to reference spectrum.
UDPGalNAc (HPLC), based on dry weight: ≥95%
UDPGalNAc (HPLC): ≥97% area%
Water (K. Fischer): ≤8%
Na (flame photometer): 6.0 - 8.0%
UDPGlucNAc (¹H-NMR): ≤1%
UMP (HPLC): ≤1 area%
UDP (HPLC): ≤1 area%
Heavy metals (as Pb): ≤25 ppm
Proteins (Bradford): ≤100 μg/g
Endotoxine: ≤0.5 EU/mg
Bioburden: ≤100 CFU/g
Stability: At +2 to +8°C within specification range for 36 months.", "Country": "XG", "Code": "Specification", "Name": "Specification" }, { "Language": "en", "Value": "CAS Number: 91183-98-1
Formula: C₁₇H₂₅N₃O₁₇P₂ Na₂
Molar mass:
UDPGalNAc: 607.4 g/mol
UDPGalNAc-Na₂: 651.32 g/mol", "Country": "XG", "Code": "Properties", "Name": "Properties" } ] } } ] }