{
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"ID": "3.2.17.2.67.0",
"ProductType": "Others",
"BrandName": "UDP-N-Acetylgalactosamine",
"ProductNameAddition": "sodium salt, lyophilizate",
"RegulatoryDisclaimer1": "For further processing only.",
"DisclaimerGroup1": "",
"RegulatoryDisclaimer2": null,
"DisclaimerGroup2": null,
"RegulatoryDisclaimer3": null,
"SampleType": [
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"LicenseDisclaimers": [
{
"Order": "78",
"Identifier": "1403506419168",
"LongText": "The sale of the Product does not exhaust or grant any rights in third party patents including patents of companies of the F. Hoffmann - La Roche AG group of companies, in particular, for the use of modified antibodies obtained by using the product."
}
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"Clone": "",
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""
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""
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"ProductNameGlobal": "UDP-N-Acetylgalactosamine"
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"ProductImageDetails": {
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"ImageType": "Image main"
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"Product2Taxonomy": {
"Product2TaxonomyReferences": [
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"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"StructureNodeStatus": "valid",
"NodeName": "In vitro Glycoengineering",
"NodeID": "02-0052"
},
{
"StructureSystemIdentifier": "OWP_Product_Types",
"StructureSystemName": "Product Types",
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"NodeName": "Activated sugars",
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"Product2Materials": {
"P2MaterialReferences": [
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"MaterialNum": "06369855103",
"MaterialDescription": "UDP-N-Acetylgalactosamine, Disodium",
"RegisteredProductName": "UDP-N-Acetylgalactosamine",
"GTIN": "",
"ProductCategoryText": "Reagents, kits",
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"OrderInformation": "Unit of measure is \"gram\"."
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"ProductSpec": [
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"ProductSpecVariant": {
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"Language": "en",
"Value": "Unit of measure is \"gram\".",
"Country": "XG",
"Code": "CB - Order Information",
"Name": "CB - Order Information"
},
{
"Language": "en",
"Value": "UDP-N-Acetylgalactosamine is an activated sugar, and can be used for
in vitro glycoengineering of glycoproteins,
e.g. therapeutic proteins.",
"Country": "XG",
"Code": "Positioning",
"Name": "Positioning"
},
{
"Language": "en",
"Value": "UDP-N-Acetylgalactosamine is a disodium salt, provided as a white, lyophilized substance.",
"Country": "XG",
"Code": "Product Description",
"Name": "Product Description"
},
{
"Language": "en",
"Value": "Benefits of using
in vitro glycoengineering to modify glycosylation of therapeutic proteins:
- Time- and cost-saving generation of glycan variants to develop improved drugs
- Optimized glycosylation without compromising other CQAs or product yield
- Improved lot-to-lot consistency to reduce risk of product quality variation and resulting delays
- Generation of glycoprofiles which may not otherwise be generated
- Streamlined analytics in comparability studies
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"Country": "XG",
"Code": "Benefits",
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{
"Language": "en",
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{
"Language": "en",
"Value": "
Appearance: White powder
Solution (c = 100 mg/mL water): Clear, colorless
Identity (
1H-NMR): spectrum conforms to reference spectrum.
UDPGalNAc (HPLC), based on dry weight: ≥95%
UDPGalNAc (HPLC): ≥97% area%
Water (K. Fischer): ≤8%
Na (flame photometer): 6.0 - 8.0%
UDPGlucNAc (
1H-NMR): ≤1%
UMP (HPLC): ≤1 area%
UDP (HPLC): ≤1 area%
Heavy metals (as Pb): ≤25 ppm
Proteins (Bradford): ≤100 μg/g
Endotoxine: ≤0.5 EU/mg
Bioburden: ≤100 CFU/g
Stability: At +2 to +8°C within specification range for 36 months.",
"Country": "XG",
"Code": "Specification",
"Name": "Specification"
},
{
"Language": "en",
"Value": "
CAS Number: 91183-98-1
Formula: C
17H
25N
3O
17P
2 Na
2Molar mass:UDPGalNAc: 607.4 g/mol
UDPGalNAc-Na
2: 651.32 g/mol",
"Country": "XG",
"Code": "Properties",
"Name": "Properties"
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}
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}