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"ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Unit of measure is \"gram\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Benefits of using in vitro glycoengineering to modify glycosylation of therapeutic proteins:
  • Time- and cost-saving generation of glycan variants to develop improved drugs
  • Optimized glycosylation without compromising other CQAs or product yield
  • Improved lot-to-lot consistency to reduce risk of product quality variation and resulting delays
  • Generation of glycoprofiles which may not otherwise be generated
  • Streamlined analytics in comparability studies
", "Name": "Benefits" }, { "Language": "en", "Value": "No animal-derived material is added in fermentation, purification and final formulation of this enzyme.", "Name": "Quality Control" }, { "Language": "en", "Value": "UDP-Galactose animal-free is an activated sugar, and can be used for in vitro glycoengineering of glycoproteins, e.g. therapeutic proteins.", "Name": "Positioning" }, { "Language": "en", "Value": "UDP-Galactose animal-free is a disodium salt, provided as a white, lyophilized substance.", "Name": "Product Description" }, { "Language": "en", "Value": "Incubation of UDP-Galactose and β-1,4-Galactosyltransferase with a glycoprotein leads to increased galactosylation of the glycoprotein.", "Name": "Applications" }, { "Language": "en", "Value": "Formula: C15H22N2O17P2Na2
Molar mass:
UDPgalactose: 566.3 g/mol
UDPgalactose di-Na: 610.3 g/mol", "Name": "Properties" }, { "Language": "en", "Value": "Appearance: White, lyophilized substance
Solution (c=100 mg/mL water): Clear, colorless
pH value: 5.0 - 7.0
UDPgal.,di-Na (A260, ε= 9.9 [Lxmmol-1xcm-1]): ≥ 80.0%
UDP-galactose (HPLC): ≥ 95.0 area%
Na (flamefotom.): 6.0-8.0%
Water (K.Fischer): ≤ 10.0%
UDP (HPLC): ≤ 1.5 area%
UMP (HPLC): ≤ 1 area%
Uridine (HPLC): ≤ 0.5 area%
UTP (HPLC): ≤ 0.2 area%
Total unknown impurities (HPLC): ≤ 1 area%
Heavy metals (as Pb): ≤ 25 ppm
Pinorg. ≤ 0.4 %
Iron (AAS): ≤ 10 ppm
Bioburden: ≤ 100 CFU/g
Stability: At +2 to +8°C within specification range for 12 months.", "Name": "Specification" } ] } } ] }

UDP-Galactose animal-free

disodium salt, lyophilizate

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