For further processing only. Others Trypsin rec GMP Grade Trypsin, rec., GMP Grade 3.1.3.7.21.1 Expressed in Pichia pastoris 03 358 658 103 3 358 658 103 03358658103 3358658103 03358658103 Trypsin rec. 3,5 MU per bottle Trypsin, recombinant Reagents, kits 3.5 MU Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "Trypsin rec. Bulk". Unit of measure is "MU". 06 369 880 103 6 369 880 103 06369880103 6369880103 06369880103 Trypsin, recombinant 1g Trypsin, recombinant Reagents, kits PC (1g = 0.23 MU) Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "Trypsin rec. Bulk". Unit of measure is "MU". EC 3.4.4.4 en 9002-07-7 en Use the animal component-free and DIN EN ISO 13485-manufactured Trypsin, recombinant, as critical raw material for the production of active pharmaceutical ingredients (API), i.e., insulin, vaccines and for cell dissociation. en Trypsin is a widely used serine protease, typically isolated from pancreas of different animals, that specifically cleaves at the C-terminus of arginine and lysine within a peptide chain. Roche has chemically synthesized a gene encoding for the amino acid sequence of Trypsin and has transformed the gene into the expression host Pichia pastoris, which expresses the recombinant Trypsin as active protease with identical properties compared to the native Trypsin.The product is manufactured according to DIN EN ISO 13485. No animal-derived products are used in the fermentation, purification and final formulation. The production process is validated resulting in a very high lot-to-lot consistency. en Appearance: Clear, colorless to slightly yellowish solution Storage buffer: HCl, 10 mmol/L; CaCl2, 20 mmol/L pH value: 2±0.5 Activity (with chromozym TRY): ≥10,800 U/mL Total activity (with chromozym TRY): 3.5 MU ±10% Specific activity: ≥180 U/mg Protein: 70±10 mg/mL Purity (RP-HPLC): ≤20% α-trypsin, ≥70% β-trypsin, corresponds to master lot Bioburden: ≤100 CFU/mL Stability: At -15 to -25°C within specification range for 36 months. en

Secure and efficient protein production with Trypsin, rec., GMP Grade

Supporting your manufacturing challenges with exceptional enzyme quality and reproducibility

Address the rigorous demands of biopharmaceutical manufacturing with a serine protease designed for safety and efficiency. Roche CustomBiotech offers a recombinant trypsin expressed in Pichia pastoris, ensuring the enzyme is produced as a fully active protease. This expression system delivers a product with specificity equivalent to native trypsin, but without the regulatory risks associated with animal-derived raw materials.

Secure your supply chain and streamline your downstream processing with a highly pure, animal-free solution.

Key benefits:

Mitigate risk: Minimize the risk of animal-origin viruses and cross-contamination by using a completely animal-free production system.

Ensure purity: Reduce the burden on your purification steps by minimizing host cell protein (HCP) contamination in your final API.

Enhance consistency: Increase process reliability with a GMP Grade enzyme that offers reproducible performance and high lot-to-lot consistency

rdoe_persona_userprofile

rdoe_persona_select_up

Trypsin, rec., GMP Grade

Secure and efficient protein production with Trypsin, rec., GMP Grade

Supporting your manufacturing challenges with exceptional enzyme quality and reproducibility

Ordering information

Technical documents

Contact us

rdoe_persona_userprofile

rdoe_persona_select_up

Trypsin, rec., GMP Grade

Secure and efficient protein production with Trypsin, rec., GMP Grade

Supporting your manufacturing challenges with exceptional enzyme quality and reproducibility

Related pages

Downloads

Ordering information

Technical documents

Contact us