{
"ProductData": {
"ID": "3.6.14.7.2.1",
"ProductType": "Others",
"BrandName": "RNase A",
"ProductNameAddition": "from bovine pancreas, lyophilizate, powder",
"RegulatoryDisclaimer1": "For further processing only.",
"DisclaimerGroup1": "",
"RegulatoryDisclaimer2": null,
"DisclaimerGroup2": null,
"RegulatoryDisclaimer3": null,
"SampleType": [
],
"LicenseDisclaimers": [
],
"RelatedLinks": "",
"Clone": "",
"ControlTissue": [
""
],
"ISOtypes": "",
"Species": [
""
],
"StainLocalization": [
""
],
"ProductNameGlobal": "RNase A lyophilizate"
},
"ProductImageDetails": {
"ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE_.png",
"ImageType": "Image main"
},
"Product2Taxonomy": {
"Product2TaxonomyReferences": [
{
"StructureSystemIdentifier": "OWP_Product_Types",
"StructureSystemName": "Product Types",
"NodeID": "70-037-00",
"StructureNodeStatus": "valid",
"NodeName": "Nucleases"
},
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"NodeID": "02-0136",
"StructureNodeStatus": "valid",
"NodeName": "Molecular Raw Materials"
},
{
"StructureSystemIdentifier": "OWP_Organization",
"StructureSystemName": "Organization",
"NodeID": "01-01-01-07-00",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech and LifeScience"
},
{
"StructureSystemIdentifier": "OWP_Techniques",
"StructureSystemName": "Techniques",
"NodeID": "241-00",
"StructureNodeStatus": "valid",
"NodeName": "Nucleic Acid Extraction and Purification"
},
{
"StructureSystemIdentifier": "Product_Solutions",
"StructureSystemName": "Product Solutions",
"NodeID": "520",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech"
},
{
"StructureSystemIdentifier": "Lab_Type",
"StructureSystemName": "Lab Types",
"NodeID": "180-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "Applications",
"StructureSystemName": "Applications",
"NodeID": "99-00-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "Disease_Areas",
"StructureSystemName": "Disease Areas",
"NodeID": "99-00-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "Pathogens",
"StructureSystemName": "Pathogens",
"NodeID": "99-00-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "OWP_Family",
"StructureSystemName": "Product Families",
"NodeID": "999",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "Health_Topics",
"StructureSystemName": "Health Topics",
"NodeID": "99-00-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
}
]
},
"Product2Materials": {
"P2MaterialReferences": [
{
"MaterialNum": "10154105103",
"MaterialDescription": "Ribonuclease A from Bovine Pancreas",
"RegisteredProductName": "RNase A",
"GTIN": "",
"ProductCategoryText": "Reagents, kits",
"OldMaterialNumber": "",
"PackSizePIM360": "custom fill",
"PackSizeDescPIM360": "Not Available",
"MaterialAnnotation": "CustomBiotech product. Please contact your
local representative.",
"ReadyForUse": "",
"OrderInformation": "Will be supplied as \"Ribonuclease A from Bovine Pancreas\". Unit of measure is \"g\"."
}
]
},
"Product2Products": {
"Product2ProductReference": [
]
},
"ProductSpec": [
{
"ProductSpecVariant": {
"Chapters": [
{
"Name": "CB - Order Information",
"Value": "Will be supplied as \"Ribonuclease A from Bovine Pancreas\". Unit of measure is \"g\".",
"Language": "en",
"Country": "XG",
"Code": "CB - Order Information"
},
{
"Name": "Applications",
"Value": "Use RNase A for isolation of genomic DNA. For this purpose, RNase A should be boiled before use.",
"Language": "en",
"Country": "XG",
"Code": "Applications"
},
{
"Name": "Positioning",
"Value": "Standard RNase A in lyophilized quality is an essential tool for applications requiring RNA-free DNA templates.",
"Language": "en",
"Country": "XG",
"Code": "Positioning"
},
{
"Name": "Properties",
"Value": "
CAS Number: 9001-99-4
Molecular weight: 13.7 kD
Specificity: Pyrimidine-specific endoribonuclease that acts on single-stranded RNA",
"Language": "en",
"Country": "XG",
"Code": "Properties"
},
{
"Name": "Specification",
"Value": "
Appearance: White lyophilizate
Solubility: Clear, colorless solution in water (c=1 mg/mL)
Activity: ≥50 U/mg
Unit definition: One unit produces a decrease in absorbance from A
0 to A
1 in 1 minute under assay conditions (Kunitz). A
0 to A
1 corresponds to the total conversion, A
1 being the final absorbance.
Unspecific endonucleases (λDNA): Not detectable in up to 1 μg after 4 hours incubation at +37°C.
Nicking activity (pBR322 DNA): Not detectable in up to 1 μg after 4 hours incubation at +37°C.
Proteases (A ≤0.1, 15 minutes, +37°C): Corresponds to reference
Turbidity, according to Maniatis (A
366 ≤0.100): Corresponds to reference
A280 (1 mg/mL water): 0.54-0.72
pH ≤5.0 treatment (≥3 hours): Corresponds to reference
Countries of origin: South Africa, Argentina, Australia, New Zealand, Uruguay or the United States
Stability: At +2 to +8°C within specification range for 24 months. Store dry.",
"Language": "en",
"Country": "XG",
"Code": "Specification"
}
]
}
}
]
}