{ "ProductData": { "ID": "3.6.14.7.2.1", "ProductType": "Others", "BrandName": "RNase A", "ProductNameAddition": "from bovine pancreas, lyophilizate, powder", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": "", "DisclaimerGroup2": null, "RegulatoryDisclaimer3": "", "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "RNase A lyophilizate" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "StructureNodeStatus": "valid", "NodeName": "Nucleases", "NodeID": "70-037-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Molecular Raw Materials", "NodeID": "02-0136" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "valid", "NodeName": "Nucleic Acid Extraction and Purification", "NodeID": "241-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "180-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "10154105103", "MaterialDescription": "Ribonuclease A from Bovine Pancreas", "RegisteredProductName": "RNase A", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Ribonuclease A from Bovine Pancreas\". Unit of measure is \"g\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Will be supplied as \"Ribonuclease A from Bovine Pancreas\". Unit of measure is \"g\".", "Country": "XG", "Code": "CB - Order Information", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Use RNase A for isolation of genomic DNA. For this purpose, RNase A should be boiled before use.", "Country": "XG", "Code": "Applications", "Name": "Applications" }, { "Language": "en", "Value": "Standard RNase A in lyophilized quality is an essential tool for applications requiring RNA-free DNA templates.", "Country": "XG", "Code": "Positioning", "Name": "Positioning" }, { "Language": "en", "Value": "CAS Number: 9001-99-4
Molecular weight: 13.7 kD
Specificity: Pyrimidine-specific endoribonuclease that acts on single-stranded RNA", "Country": "XG", "Code": "Properties", "Name": "Properties" }, { "Language": "en", "Value": "Appearance: White lyophilizate
Solubility: Clear, colorless solution in water (c=1 mg/mL)
Activity: ≥50 U/mg
Unit definition: One unit produces a decrease in absorbance from A₀ to A₁ in 1 minute under assay conditions (Kunitz). A₀ to A₁ corresponds to the total conversion, A₁ being the final absorbance.
Unspecific endonucleases (λDNA): Not detectable in up to 1 μg after 4 hours incubation at +37°C.
Nicking activity (pBR322 DNA): Not detectable in up to 1 μg after 4 hours incubation at +37°C.
Proteases (A ≤0.1, 15 minutes, +37°C): Corresponds to reference
Turbidity, according to Maniatis (A₃₆₆ ≤0.100): Corresponds to reference
A₂₈₀ (1 mg/mL water): 0.54-0.72
pH ≤5.0 treatment (≥3 hours): Corresponds to reference
Countries of origin: South Africa, Argentina, Australia, New Zealand, Uruguay or the United States
Stability: At +2 to +8°C within specification range for 24 months. Store dry.", "Country": "XG", "Code": "Specification", "Name": "Specification" } ] } } ] }