Pyrophosphatase, rec., GMP Grade, AOF

from yeast, expressed in E. coli, solution

Improve your yield of mRNA

Pyrophosphatase is an essential enzyme for in vitro transcription of mRNA. By hydrolyzing inorganic pyrophosphate, it shifts the equilibrium of the mRNA synthesis reaction towards the formation of mRNA.

Designed fit-for-purpose to be used in the manufacture of mRNA for therapeutics and vaccines, CustomBiotech Pyrophosphatase provides the performance, quality, and scale you need.

We have designed our manufacturing process from the master cell bank to final QC-release to exclude or minimize potential contaminants, thereby reducing overall process risk and simplifying procedures for regulatory approval.

produced using validated manufacturing and cleaning processes up to the final filling step and released under stringent final QC checks. Know that you are getting consistent quality every time.

from the generation of the master cell bank to the final filling, noanimal-derived materials are used in the process. This greatly simplifies your risk analysis.

our proprietary E. coli strain eliminates the need for antibiotics during fermentation. Therefore, allergic reactions to antibiotics is not a factor in your overall risk analysis.

tested during final QC-release for the absence of impurities such as nucleases, host-cell DNA and protein, bioburden, heavy metals, or endotoxins. Work with an enzyme at peak performance that poses no risk to downstream processing.

We work with you to provide the necessary technical documents for your regulatory submissions.

Changing reagent quality between pre-clinical development and commercialization poses a risk. Secure your processes by using the best available quality from the start.

Reach out to your regional CustomBiotech representative for more information
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for certificates, method sheets (instructions for use), safety data sheets and software downloads
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