For DNA or (m)RNA isolation, Proteinase K is the enzyme of choice to remove proteins that are still present adjacent to the nucleic acids. For about 20 years, Roche has been producing this enzyme from a recombinant organism and making it available in a highly reproducible quality that became the gold standard in the industry.
Special emphasis was placed on the testing for contaminating impurities, such as nucleases and DNA. Designed fit-for-purpose to isolate nucleic acids, Roche CustomBiotech Proteinase K, PCR Grade, provides the performance, quality, and scale you need.
We have designed our manufacturing process from the master cell bank to final QC-release to exclude or minimize potential contaminants, thereby reducing overall process risk and simplifying procedures for regulatory approval.