{
"ProductData": {
"ID": "3.1.3.1.13.1",
"ProductType": "Others",
"BrandName": "Pronase",
"ProductNameAddition": "from
Streptomyces griseus, lyophilizate",
"RegulatoryDisclaimer1": "For further processing only.",
"DisclaimerGroup1": "",
"RegulatoryDisclaimer2": null,
"DisclaimerGroup2": null,
"RegulatoryDisclaimer3": null,
"SampleType": [
],
"LicenseDisclaimers": [
],
"RelatedLinks": "",
"Clone": "",
"ControlTissue": [
""
],
"ISOtypes": "",
"Species": [
""
],
"StainLocalization": [
""
],
"ProductNameGlobal": "Pronase lyophilizate"
},
"ProductImageDetails": {
"ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE_.png",
"ImageType": "Image main"
},
"Product2Taxonomy": {
"Product2TaxonomyReferences": [
{
"StructureSystemIdentifier": "OWP_Product_Types",
"StructureSystemName": "Product Types",
"NodeID": "70-044-00",
"StructureNodeStatus": "valid",
"NodeName": "Proteases"
},
{
"StructureSystemIdentifier": "OWP_Organization",
"StructureSystemName": "Organization",
"NodeID": "01-01-01-07-00",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech and LifeScience"
},
{
"StructureSystemIdentifier": "Product_Solutions",
"StructureSystemName": "Product Solutions",
"NodeID": "520",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech"
},
{
"StructureSystemIdentifier": "Lab_Type",
"StructureSystemName": "Lab Types",
"NodeID": "180-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "Applications",
"StructureSystemName": "Applications",
"NodeID": "99-00-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "OWP_Techniques",
"StructureSystemName": "Techniques",
"NodeID": "999-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "Disease_Areas",
"StructureSystemName": "Disease Areas",
"NodeID": "99-00-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "Pathogens",
"StructureSystemName": "Pathogens",
"NodeID": "99-00-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "OWP_Family",
"StructureSystemName": "Product Families",
"NodeID": "999",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "Health_Topics",
"StructureSystemName": "Health Topics",
"NodeID": "99-00-00",
"StructureNodeStatus": "invalid",
"NodeName": ""
},
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"NodeID": "02-0133",
"StructureNodeStatus": "valid",
"NodeName": "Cell and Gene Therapy"
},
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"NodeID": "02-0112",
"StructureNodeStatus": "valid",
"NodeName": "Protease Portfolio"
},
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"NodeID": "02-0014",
"StructureNodeStatus": "valid",
"NodeName": "Enzymes"
},
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"NodeID": "02-0008",
"StructureNodeStatus": "valid",
"NodeName": "Biologics"
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]
},
"Product2Materials": {
"P2MaterialReferences": [
{
"MaterialNum": "10165913103",
"MaterialDescription": "Pronase from Streptomyces griseus",
"RegisteredProductName": "Pronase",
"GTIN": "",
"ProductCategoryText": "Reagents, kits",
"OldMaterialNumber": "",
"PackSizePIM360": "100 g",
"PackSizeDescPIM360": "Not Available",
"MaterialAnnotation": "CustomBiotech product. Please contact your
local representative.",
"ReadyForUse": "",
"OrderInformation": "Will be supplied as \"Pronase from Streptomyces griseus\". Unit of measure is \"g\"."
}
]
},
"Product2Products": {
"Product2ProductReference": [
]
},
"ProductSpec": [
{
"ProductSpecVariant": {
"Chapters": [
{
"Name": "CB - Order Information",
"Value": "Will be supplied as \"Pronase from Streptomyces griseus\". Unit of measure is \"g\".",
"Language": "en",
"Country": "XG",
"Code": "CB - Order Information"
},
{
"Name": "Quality Control",
"Value": "Contaminants are ≤0.002 U DNase/RNase per mg lyophilizate.",
"Language": "en",
"Country": "XG",
"Code": "Quality Control"
},
{
"Name": "Applications",
"Value": "Use Pronase for:
- Total degradation of proteins during isolation of DNA and RNA
- Total hydrolysis of proteins for technical purposes
- Tissue dissociation in conjunction with collagenases and trypsin
- Production of glycopeptides from purified glycoproteins
",
"Language": "en",
"Country": "XG",
"Code": "Applications"
},
{
"Name": "Product Description",
"Value": "Pronase is a mixture of several nonspecific endo- and exoproteases that digest proteins down to single amino acids. Resolves carboxylic acids and alcohols.",
"Language": "en",
"Country": "XG",
"Code": "Product Description"
},
{
"Name": "Background Information",
"Value": "The preparation contains approximately 20% calcium acetate.",
"Language": "en",
"Country": "XG",
"Code": "Background Information"
},
{
"Name": "Positioning",
"Value": "Pronase is used for total degradation of proteins.",
"Language": "en",
"Country": "XG",
"Code": "Positioning"
},
{
"Name": "Specification",
"Value": "
Appearance: Almost white lyophilizate
Activity (+40°C, casein): ≥6,000 U/g lyophilizate
Contaminants:
DNases/RNases: ≤0.002 U/mg lyphilizate
Stability: At +2 to +8°C within specification range for 12 months. Store dry.",
"Language": "en",
"Country": "XG",
"Code": "Specification"
},
{
"Name": "Properties",
"Value": "
CAS Number: 9036-06-6
pH optimum: 6.0-7.5",
"Language": "en",
"Country": "XG",
"Code": "Properties"
}
]
}
}
]
}