{ "ProductData": { "ID": "3.1.3.1.13.1", "ProductType": "Others", "BrandName": "Pronase", "ProductNameAddition": "from Streptomyces griseus, lyophilizate", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": null, "DisclaimerGroup2": null, "RegulatoryDisclaimer3": null, "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "Pronase lyophilizate" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE_.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeID": "70-044-00", "StructureNodeStatus": "valid", "NodeName": "Proteases" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeID": "01-01-01-07-00", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeID": "520", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeID": "180-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeID": "999-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeID": "999", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0133", "StructureNodeStatus": "valid", "NodeName": "Cell and Gene Therapy" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0112", "StructureNodeStatus": "valid", "NodeName": "Protease Portfolio" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0014", "StructureNodeStatus": "valid", "NodeName": "Enzymes" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0008", "StructureNodeStatus": "valid", "NodeName": "Biologics" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "10165913103", "MaterialDescription": "Pronase from Streptomyces griseus", "RegisteredProductName": "Pronase", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "100 g", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Pronase from Streptomyces griseus\". Unit of measure is \"g\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Name": "CB - Order Information", "Value": "Will be supplied as \"Pronase from Streptomyces griseus\". Unit of measure is \"g\".", "Language": "en", "Country": "XG", "Code": "CB - Order Information" }, { "Name": "Quality Control", "Value": "Contaminants are ≤0.002 U DNase/RNase per mg lyophilizate.", "Language": "en", "Country": "XG", "Code": "Quality Control" }, { "Name": "Applications", "Value": "Use Pronase for:

• Total degradation of proteins during isolation of DNA and RNA
• Total hydrolysis of proteins for technical purposes
• Tissue dissociation in conjunction with collagenases and trypsin
• Production of glycopeptides from purified glycoproteins

", "Language": "en", "Country": "XG", "Code": "Applications" }, { "Name": "Product Description", "Value": "Pronase is a mixture of several nonspecific endo- and exoproteases that digest proteins down to single amino acids. Resolves carboxylic acids and alcohols.", "Language": "en", "Country": "XG", "Code": "Product Description" }, { "Name": "Background Information", "Value": "The preparation contains approximately 20% calcium acetate.", "Language": "en", "Country": "XG", "Code": "Background Information" }, { "Name": "Positioning", "Value": "Pronase is used for total degradation of proteins.", "Language": "en", "Country": "XG", "Code": "Positioning" }, { "Name": "Specification", "Value": "Appearance: Almost white lyophilizate
Activity (+40°C, casein): ≥6,000 U/g lyophilizate
Contaminants:
DNases/RNases: ≤0.002 U/mg lyphilizate
Stability: At +2 to +8°C within specification range for 12 months. Store dry.", "Language": "en", "Country": "XG", "Code": "Specification" }, { "Name": "Properties", "Value": "CAS Number: 9036-06-6
pH optimum: 6.0-7.5", "Language": "en", "Country": "XG", "Code": "Properties" } ] } } ] }