{ "ProductData": { "ID": "3.1.5.4.6.4", "ProductType": "Others", "BrandName": "Peroxidase (POD), Grade II", "ProductNameAddition": "from horse radish, lyophilizate", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": null, "DisclaimerGroup2": null, "RegulatoryDisclaimer3": null, "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "Peroxidase POD Grade II" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Enzymes", "NodeID": "02-0014" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "StructureNodeStatus": "valid", "NodeName": "Oxidases", "NodeID": "70-040-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Clinical Chemistry Raw Materials", "NodeID": "02-0011" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "valid", "NodeName": "Carbohydrate Testing", "NodeID": "01-00-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "valid", "NodeName": "Lipid Testing", "NodeID": "11-00-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "valid", "NodeName": "Nitrogen Metabolism Testing", "NodeID": "16-00-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "180-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "11378783103", "MaterialDescription": "Peroxidase (POD), Grade II,Horse-radish", "RegisteredProductName": "Peroxidase (POD), Grade II", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Peroxidase (POD), Grade II, Horse-radish\". Unit of measure for custom fill is \"MU\"." }, { "MaterialNum": "11378783101", "MaterialDescription": "Peroxidase (POD), Grade II,Horse-radish", "RegisteredProductName": "Peroxidase (POD), Grade II", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "1 MU package", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Peroxidase (POD), Grade II, Horse-radish\". Unit of measure for 1 MU-package is “piece”." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Will be supplied as \"Peroxidase (POD), Grade II, Horse-radish\".
11378783101: Unit of measure for 1 MU-package is “piece”.
11378783103: Unit of measure for custom fill is \"MU\".", "Country": "XG", "Code": "CB - Order Information", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Use Peroxidase (POD), Grade II, for the oxidation of reduced dyes in the indicator reaction of many diagnostic tests, e.g., for the determination of blood glucose, triglycerides or lactate. It may also be used as a marker enzyme for enzyme immunoassays (EIA).", "Country": "XG", "Code": "Applications", "Name": "Applications" }, { "Language": "en", "Value": "Appearance: Red-brown lyophilizate
Solubility: Clear, red-brown solution in water (c=10 mg/mL)
pH value (c=10 mg/mL in water): 6.6-7.6
Activity: ≥200 U/mg lyophilizate
Purity number (A₄₀₃/A₂₇₅): 2.0-3.5
A₅₀₀ (100 U/mL): ≤0.120
Contaminants (expressed as percentage of Peroxidase activity):
ATPase: ≤0.001
Catalase: ≤0.7
Contaminating oxidases: ≤0.00005
Phosphatase, acidic: ≤0.001
Glucose: ≤0.25 μg/mg lyophilizate
Stability: At +2 to +8°C within specification range for 24 months. Store dry.", "Country": "XG", "Code": "Specification", "Name": "Specification" }, { "Language": "en", "Value": "Nomenclature: Donor:hydrogen-peroxide oxidoreductase
CAS Number: 9003-99-0
Molecular weight: 40 kD
Structure: Glycoprotein with one mole of protoheme IX
Isoelectric point: 7.2
Rate constants:
a) Hydrogen acceptors:
H₂O₂ 9 x 10⁸ [L x mol^-1 x s^-1]
methyl peroxide 1.5 x 10⁶ [L x mol^-1 x s^-1]
ethyl peroxide 3.6 x 10⁶ [L x mol^-1 x s^-1]
b) Hydrogen donors: Many
Inhibitors: Cyanide, sulfide, fluoride, azide, hydroxylamine, hydroxyl ions
Activators: Peroxidation of o-dianisidine is accelerated by ammonia, pyridine, imidazole at pH values >7.0
pH optimum: 6.0-6.5 (see figure)
Temperature dependence: See figure
pH stability: 4.0-10.0 (see figure)
Thermal stability: Up to +40°C (see figure)
Specificity: Peroxidase is specific for the hydrogen acceptor; only H₂O₂, methyl- and ethylperoxides are active. In contrast the enzyme is not specific for the hydrogen donor. A large number of phenols, aminophenols, diamines, indophenols, leucocyte dyes, ascorbate and several amino acids react.", "Country": "XG", "Code": "Properties", "Name": "Properties" } ] } } ] }