{ "ProductData": { "RelatedLinks": "", "RegulatoryDisclaimer1": "For further processing only.", "RegulatoryDisclaimer2": "", "StainLocalization": [ "" ], "ProductType": "Others", "DisclaimerGroup2": null, "ProductNameGlobal": "NucleoMix dTTP PCR Grade 40 mM", "DisclaimerGroup1": "Non-IVD", "ControlTissue": [ "" ], "BrandName": "NucleoMix (dTTP), PCR Grade", "LicenseDisclaimers": [ ], "Isotypes": "", "RegulatoryDisclaimer3": "", "ID": "3.6.5.1.6.12", "ProductNameAddition": "sodium salt, 40 mM (10 mmol/L each dNTP)", "Species": [ "" ], "Clone": "" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxomony": { "Product2TaxomonyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Nucleotides", "NodeID": "02-0018" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeName": "Deoxyucleotides", "NodeID": "70-015-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeName": "Nucleomix", "NodeID": "639" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Molecular Raw Materials", "NodeID": "02-0136" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeName": "PCR/qPCR", "NodeID": "210-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeName": "RT-PCR/qRT-PCR", "NodeID": "300-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeName": "Manufacturing", "NodeID": "180-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "03186083103", "MaterialDescription": "Nucleomix(10 mmol/l,with TTP)", "RegisteredProductName": "NucleoMix (dTTP), PCR Grade", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "100 mL", "PackSizeDescPIM360": "", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Nucleomix (10 mmol/L, with dTTP)\". Unit of measure is \"mL\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Will be supplied as \"Nucleomix (10 mmol/L, with dTTP)\". Unit of measure is \"mL\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "NucleoMix (dTTP), PCR Grade, is designed for amplification reactions where high-quality reagents are required, such as for in vitro diagnostics. The ready-to-use mix eliminates process steps.", "Name": "Applications" }, { "Language": "en", "Value": "NucleoMix (dTTP), PGR Grade, is supplied in sealed and CO2-proof bottles to ensure a stable pH during shipment on dry ice. The manufacturing process is fully validated including the final filling step. The pH is adjusted to match conditions for amplification.", "Name": "Product Description" }, { "Language": "en", "Value": "Manufactured under GMP (Good Manufacturing Practice) regulations.", "Name": "Quality Control" }, { "Language": "en", "Value": "GMP-manufactured NucleoMixes from the leading manufacturer of nucleotides for outstanding, consistent performance in amplification reactions.", "Name": "Positioning" }, { "Language": "en", "Value": "Appearance: Clear, colorless solution
pH value: 8.1-8.5
Concentration (sum, 1 μmol ≙ 10.7 A260 units, pH 7.0): 40-44 mmol/L
Identity (HPLC diode array detector):
dATP: 9-12 mmol/L
dCTP: 9-12 mmol/L
dGTP: 9-12 mmol/L
dTTP: 9-12 mmol/L
dNTP (HPLC, sum of 4 peaks): ≥99 area%
dNDP (HPLC, sum of 4 peaks): ≤0.9 area%
DNases/RNases: Negative
Nicking activity: Negative
Function test in RT-PCR (RNA, human dystrophin, and mouse β-actin gene): Corresponds to specification
Stability: At -15 to -25°C within specification range for 35 months.", "Name": "Specification" } ] } } ] }

NucleoMix (dTTP), PCR Grade

sodium salt, 40 mM (10 mmol/L each dNTP)

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