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{
"ProductData": {
"RelatedLinks": "",
"RegulatoryDisclaimer1": "For further processing only.",
"RegulatoryDisclaimer2": "",
"StainLocalization": [
""
],
"ProductType": "Others",
"DisclaimerGroup2": null,
"ProductNameGlobal": "Neuraminidase exo-alpha-Sialidase",
"DisclaimerGroup1": "Non-IVD",
"ControlTissue": [
""
],
"BrandName": "Neuraminidase (exo-α-Sialidase)",
"LicenseDisclaimers": [
{
"Order": "78",
"Identifier": "1403506419168",
"LongText": "The sale of the Product does not exhaust or grant any rights in third party patents including patents of companies of the F. Hoffmann - La Roche AG group of companies, in particular, for the use of modified antibodies obtained by using the product."
}
],
"Isotypes": "",
"RegulatoryDisclaimer3": "",
"ID": "3.1.1.2.20.1",
"ProductNameAddition": "from Vibrio cholerae, solution",
"Species": [
""
],
"Clone": ""
},
"ProductImageDetails": {
"ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png",
"ImageType": "Image main"
},
"Product2Taxomony": {
"Product2TaxomonyReferences": [
{
"StructureSystemIdentifier": "OWP_Product_Solutions",
"StructureSystemName": "OWP Product Solutions",
"NodeName": "CustomBiotech",
"NodeID": "520"
},
{
"StructureSystemIdentifier": "OWP_Product_Types",
"StructureSystemName": "OWP Product Types",
"NodeName": "Raw Materials->Glycosidases",
"NodeID": "70-024-00"
},
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"NodeName": "CustomBiotech->In vitro Glycoengineering",
"NodeID": "02-0052"
},
{
"StructureSystemIdentifier": "OWP_Organization",
"StructureSystemName": "OWP Organization",
"NodeName": "Roche Diagnostics Solution (RDS)->Customer Areas->Core lab->CustomBiotech and LifeScience",
"NodeID": "01-01-01-07-00"
},
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"NodeName": "CustomBiotech->Enzymes",
"NodeID": "02-0014"
},
{
"StructureSystemIdentifier": "Product_Solutions",
"StructureSystemName": "Product Solutions",
"NodeName": "CustomBiotech",
"NodeID": "520"
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},
"Product2Materials": {
"P2MaterialReferences": [
{
"MaterialNum": "11087096103",
"MaterialDescription": "Neuraminidase (Sialidase)",
"RegisteredProductName": "Neuraminidase (exo-?-Sialidase)",
"GTIN": "",
"ProductCategoryText": "Reagents, kits",
"OldMaterialNumber": "",
"PackSizePIM360": "custom fill",
"PackSizeDescPIM360": "",
"MaterialAnnotation": "CustomBiotech product. Please contact your local representative.",
"ReadyForUse": "",
"OrderInformation": "Will be supplied as \"Neuraminidase (Sialidase)\". Unit of measure is \"U\"."
}
]
},
"Product2Products": {
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},
"ProductSpec": [
{
"ProductSpecVariant": {
"Chapters": [
{
"Language": "en",
"Value": "Neuraminidase hydrolyzes terminal N- or O-acetylneuraminic acids which are α2,3-, α2,6-, α2,8- linked to oligosaccharides, polysaccharides, mucopolysaccharides, glycoproteins, and glycolipids. For the hydrolysis of glycolipids, the presence of a detergent is necessary. Roche's Neuraminidase is very well suited for structural research studies on glycoconjugates and for hydrolytic cleavage of sialic acid from biological material.",
"Name": "Applications"
},
{
"Language": "en",
"Value": "Will be supplied as \"Neuraminidase (Sialidase)\". Unit of measure is \"U\".",
"Name": "CB - Order Information"
},
{
"Language": "en",
"Value": "Neuraminidase is a glycohydrolase.",
"Name": "Positioning"
},
{
"Language": "en",
"Value": "Neuraminidase hydrolyzes terminal N- or O-acyl-neuraminic acids that are α2,3-, α2,6-, or α2,8-linked to galactose, Hex, NAc, or N- or O-acylated neuraminyl residues in oligosaccharides/glycoconjugates or colominic acid. Relative rate of cleavage is α2→3 >α2→6 >α2→8, determined on bonds in tri- and tetrasaccharides.",
"Name": "Product Description"
},
{
"Language": "en",
"Value": "CAS Number: 9001-67-6 Molecular weight: Approximately 95 kD pH optimum: 5.5-6.2 Specific activity: Approximately 20 U/mg total protein (approximately 40 U/mg enzyme protein at +37°C) and pH 5.5 with N-acetyl-neuraminosyl-D-lactose as the substrate.",
"Name": "Properties"
},
{
"Language": "en",
"Value": "Appearance: Clear, colorless solution Contents (after blending with Micr-O-protect® and EDTA): Natrium acetate, 50 mmol/L; NaCl, 154 mmol/L; CaCl2, 9 mmol/L; EDTA, 10 mmol/L; Micr-O-protect® 0.1% (w/v) pH value: 5.0-6.0 Activity (+37°C, with N-acetylneuraminyl-lactose): ≥1.0 U/mL Stability: At +2 to +8°C within specification range for 18 months.",
"Name": "Specification"
}
]
}
}
]
}