For further processing into medical devices, IVD and pharmaceutical products only. Others N1-Methyl-Pseudo-UTP GMP Grade AOF V2 N1-Methyl-Pseudo-UTP, GMP Grade, AOF, V2 PID00001044 sodium salt, 100 mM, solution 10 490 896 103 10490896103 N1-Me-psUTP, pH8.3, GMP Grade, AOF,V2 N1-Me-psUTP, pH8.3, GMP Grade, AOF,V2 Reagents, kits 100 mL Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "N1-Me-psUTP, pH8.3, GMP Grade, AOF, V2". Unit of measure is "mL". 1428903-59-6 (free acid) en Appearance: Clear, colorless solution pH value: 8.1–8.5 N1-Methyl-UTP (A271; pH 7.0 ε= 7.3 [L x mmol–1 x cm–1]): 95-105 mmol/L N1-Methyl-UTP (HPLC): ≥ 98.5 area% Identity (HPLC-MS): Corresponds DNases/RNases: Negative Nicking activity: Negative Functional transcription assay: Corresponds to specification Proteases: Not detectable Exonucleases: Not detectable Endotoxins: ≤ 2 EU/mL Bioburden: ≤ 5 CFU/mL Heavy metals (Ni, Co, V): ≤ 10 ppm Stability: At –15 to –25°C within specification range for 24 months. en Modified UTP for the use in mRNA synthesis. en This modified UTP can replace UTP in in-vitro-transcription reactions, e.g. for manufacturing mRNA therapeutics and vaccines. This RNA modification provides enhanced protein expression and reduced unwanted immunogenicity against the mRNA molecule itself. Its efficacy has been proven by its use in COVID-19 vaccines. en

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N¹-Methyl-Pseudo-UTP, GMP Grade, AOF

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