For further processing only. Others N1-Methyl-Pseudo-UTP GMP Grade AOF N1-Methyl-Pseudo-UTP, GMP Grade, AOF PID00000323 sodium salt, 100 mM, solution 09744878103 Me-psUTP,100mM pH8.3 GMP Grade AOF,100mL Me-psUTP,100mM pH8.3 GMP Grade AOF,100mL Reagents, kits 100 mL Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "Me-psUTP,100mM pH8.3 GMP Grade AOF,100mL". Unit of measure is "mL" 09744762103 Me-psUTP,100mM pH8.3 GMP Grade AOF, 1 mL Me-psUTP,100mM pH8.3 GMP Grade AOF, 1 mL Reagents, kits 1.0 mL Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "Me-psUTP,100mM pH8.3 GMP Grade AOF, 1 mL". Unit of measure is "piece" 1428903-59-6 (free acid) en Modified UTP for the use in mRNA synthesis. en This modified UTP can replace UTP in in-vitro-transcription reactions, e.g. for manufacturing mRNA therapeutics and vaccines. This RNA modification provides enhanced protein expression and reduced unwanted immunogenicity against the mRNA molecule itself. Its efficacy has been proven by its use in COVID-19 vaccines. en Use this modified UTP for the synthesis of mRNA for therapeutics or vaccines. It is designed to meet the specific needs of the pharmaceutical industry (fit-for-purpose):animal-origin-free (AOF)ß-Lactam-antibiotic freeextended testing for impuritiesmanufactured under GMP en Appearance: Clear, colorless solutionpH value: 8.1–8.5N1-Methyl-UTP (A271; pH 7.0 ε= 7.3 [L x mmol–1 x cm–1]): 100–110 mmol/LN1-Methyl-UTP (HPLC): ≥ 98.5 area%Identity (HPLC-MS): CorrespondsDNases/RNases: NegativeNicking activity: NegativeFunctional transcription assay: Corresponds to specificationProteases: Not detectableExonucleases: Not detectableEndotoxins: ≤ 2 EU/mLBioburden: ≤ 5 CFU/mLHeavy metals (Ni, Co, V): ≤ 10 ppmStability: At –15 to –25°C within specification range for 24 months. en