{ "ProductData": { "ID": "3.7.9.16.1.2", "ProductType": "Others", "BrandName": "MAB<H-S-Amy>M-Tu66C7 IgG", "ProductNameAddition": "lyophilizate", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": null, "DisclaimerGroup2": null, "RegulatoryDisclaimer3": null, "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "MAB H-S-Amy M-Tu66C7 IgG" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "StructureNodeStatus": "valid", "NodeName": "Antibodies", "NodeID": "70-058-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Clinical Chemistry Raw Materials", "NodeID": "02-0011" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "valid", "NodeName": "Enzyme Testing", "NodeID": "06-00-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "180-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "11543601103", "MaterialDescription": "MAKM-Tu66C7-IgG(BR)SQ", "RegisteredProductName": "MABM-Tu66C7 IgG", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"MAK<H-S-Amy>M-Tu66C7-IgG(BR)SQ\". Unit of measure is \"g active ingredient\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Will be supplied as \"MAK<H-S-Amy>M-Tu66C7-IgG(BR)SQ\". Unit of measure is \"g active ingredient\".", "Country": "XG", "Code": "CB - Order Information", "Name": "CB - Order Information" }, { "Language": "en", "Value": "The combination of MAB<H-S-Amy>Tu88E8 and MAB<H-S-Amy>Tu66C7 inhibits the human salivary α-amylase ≥97% while maintaining the activity of the pancreatic h-α-amylase.", "Country": "XG", "Code": "Applications", "Name": "Applications" }, { "Language": "en", "Value": "Immunogen: Human salivary amylase
Spleen donor: Mouse Balb/c
Antibody class: IgG1, kappa
Clone: Tu66C7
Cross reactivity to h-pancreas α-amylase: ≤1 U/gW", "Country": "XG", "Code": "Product Description", "Name": "Product Description" }, { "Language": "en", "Value": "For measurement of acute pancreatitis (pancreatic α-amylase) in human serum and urine selective blocking of salivary α-amylase isoenzyme is achieved in the presence of the pancreatic h-α-amylase.
Qualified for the cobas^® platforms.", "Country": "XG", "Code": "Positioning", "Name": "Positioning" }, { "Language": "en", "Value": "MAB<H-S-Amy>M-Tu66C7 IgG fraction is purified by chromatography and lyophilized from a solution containing protein (≥20 mg/mL), potassium-phosphate buffer and NaCl. No preservatives are added.", "Country": "XG", "Code": "Properties", "Name": "Properties" }, { "Language": "en", "Value": "Appearance: White lyophilizate
Solubility: Clear colorless solution in NaCl, 0.9% (c=10 mg/mL)
Protein (Biuret): ≥0.7 mg/mg lyophilizate
Purity (HPLC / Mono Q): ≥90 area%
Function testing (synergetic effects at +37°C):
h salivary amylase + MAB : ≤3% amylase activity
h pancreas amylase + MAB <S-AMY>: ≥98% amylase activity
Stability: At -15 to -25°C within specification range for 24 months. Avoid repeated freezing and thawing.", "Country": "XG", "Code": "Specification", "Name": "Specification" } ] } } ] }