{ "ProductData": { "RelatedLinks": "", "RegulatoryDisclaimer1": "For further processing only.", "RegulatoryDisclaimer2": "", "StainLocalization": [ "" ], "ProductType": "Others", "DisclaimerGroup2": null, "ProductNameGlobal": "MAB CK-MM Mix", "DisclaimerGroup1": "Non-IVD", "ControlTissue": [ "" ], "BrandName": "MAB<CK-MM>Mix", "LicenseDisclaimers": [ ], "Isotypes": "", "RegulatoryDisclaimer3": "", "ID": "3.7.9.6.13.1", "ProductNameAddition": "frozen solution", "Species": [ "" ], "Clone": "" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxomony": { "Product2TaxomonyReferences": [ { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeName": "Antibodies", "NodeID": "70-058-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Clinical Chemistry Raw Materials", "NodeID": "02-0011" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeName": "Cardiac Testing", "NodeID": "02-00-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeName": "Manufacturing", "NodeID": "180-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeName": "NOT APPLICABLE", "NodeID": "999-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeName": "NOT APPLICABLE", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "04688457103", "MaterialDescription": "Mab Mix", "RegisteredProductName": "MAB Mix", "GTIN": "07613336132197", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "1 mL, 10 mL, 50 mL, 100 mL, 1000 mL", "PackSizeDescPIM360": "", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Mab<CK-MM>Mix\". Unit of measure is \"L\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Immunogen: Human creatinine kinase isoenzyme MM (h-CK-MM)
Inhibitor capacity (for information only):
4500 U/L CK-MM: ≥99.6%
300 U/L CK-BB: ± 5%", "Name": "Product Description" }, { "Language": "en", "Value": "Will be supplied as \"Mab<CK-MM>Mix\". Unit of measure is \"L\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "MAB<CK-MM>Mix is a main compound of the CK-MB assay.", "Name": "Applications" }, { "Language": "en", "Value": "Human creatine kinase isoenzyme CK-MB consist of two subunits: CK-M and CK-B. By inhibiting the CK-M subunit, the creatine kinase reaction is triggered exclusively by the β subunit of creatine kinase, which accounts for one-half of the activity of CK-MB.", "Name": "Background Information" }, { "Language": "en", "Value": "For measurement of human creatine kinase isoenzyme (CK-MB), which is a well established tool in confirming the diagnosis of acute myocardial infarction.", "Name": "Positioning" }, { "Language": "en", "Value": "The MAB<CK-MM>Mix consists of four highly specific monoclonal mouse antibodies directed to human creatinin kinase isoenzyme MM (h-CK-MM). The frozen solution contains protein, potassium phosphate buffer and sodium chloride. No preservative are added.", "Name": "Properties" }, { "Language": "en", "Value": "Appearance: Clear to slightly opalescent solution after thaw
pH value (+25°C): 7.4-7.6
HPLC (Mono Q, basic material): ≥80%
Protein (BCA): 10.8-13.2 mg/mL
Aggregates (TSK 3000): ≤10%
Inhibitor capacity:
CK-MM 4,500 U/L (+37°C): ≥96%
CK-BB 300 U/L (+37°C): ±5%
pH 5.5 treatment (30 minutes): Corresponds to specification
Stability: At -15 to -25°C within specification range for 36 months. Avoid repeated freezing and thawing.", "Name": "Specification" } ] } } ] }

MAB<CK-MM>Mix

frozen solution

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