Others Liberase MNP-S Liberase MNP-S Blended Proteolytic Enzyme for Tissue Dissociation. For Further Processing only. 3.5.3.3.12.5 0.2 μm filtered, lyophilizate 05 578 566 001 5 578 566 001 05578566001 5578566001 05578566001 Liberase MNP-S non GMP 35 mg Liberase MNP-S 07613336132074 Reagents, kits 35 mg Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "Liberase MNP-S". Unit of measure is "piece". EC 3.4.24.- en 9001-12-1 and 9073-78-3 en Liberase MNP-S contains highly purified collagenase class I and class II from Clostridium histolyticum. The two collagenase isoforms are blended in a precise ratio with each other and with a medium concentration of highly purified thermolysin, a neutral protease isolated from Bacillus thermoproteolyticus. en Maximum cell yield, viability, and functionalityUse of high-specific-activity blends with reduced clostripain, trypsin, and endotoxin content maximizes yield of viable, functional cells.Reduced contamination riskManufactured free of any mammalian- or avian-derived raw materials, avoiding the risk of transmission of animal diseases.High experimental reproducibilityHigh lot-to-lot consistency due to optimized enzyme fermentation and purification processes results in increased experimental reproducibility, ultimately saving time and resources.Flexible enzyme portfolioCustom sizes and blends are available upon request to better serve your unique application needs.Specific residual assayHighly sensitive assay developed specifically for detection of Liberase enzyme verifies removal from your final product. en Liberase MNP-S is designed for enzymatic dissociation of segregated tissue, enabling isolation of single cells.If the product is intended to be used in a clinical trial, the procedure must meet the applicable local laws and regulations, including the involvement of ethic commissions if necessary.Verification of suitability of product for a specific application in all aspects is in the responsibility of the applicant. en Liberase MNP-S is a highly purified enzyme blend for tissue dissociation where high purity, consistent quality, low levels of bacterial endotoxins and a sterile product are required for reproducible high cell yield and viability. en Appearance: White lyophilized cakeTotal protein content: 41.5-62.3 mg/bottle (target: 51.9 mg protein)Collagenase I b, c part of collagenase I: ≤40 area%Collagenase I content: 16.8-25.2 mg/bottle (target: 21.0 mg protein)Collagenase II content: 11.2-16.8 mg/bottle (target: 14.0 mg protein)Thermolysin/neutral protease content: 13.5-20.3 mg/bottle (target: 16.9 mg protein)Activity (Wünsch, calculated): 142-237 U/bottleActivity (thermolysin/neutral protease, calculated): 147,030-275,000 U/bottleRatio collagenase II/total collagenase: 0.3-0.5Endotoxin: ≤15 EU/mg protein en

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