{ "ProductData": { "ID": "3.2.7.1.27.1", "ProductType": "Others", "BrandName": "Leupeptin", "ProductNameAddition": "Ac-Leu-Leu-argininal x ½ H₂SO₄, synthetic", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": null, "DisclaimerGroup2": null, "RegulatoryDisclaimer3": null, "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "Leupeptin synthetic" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "StructureNodeStatus": "valid", "NodeName": "Protease inhibitors", "NodeID": "70-043-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "180-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "10528595103", "MaterialDescription": "Leupeptin, synthetic", "RegisteredProductName": "Leupeptin", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied \"Leupeptin, synthetic\". Unit of measure is \"mg\". Minimum order quantity is 1500 mg." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Leupeptin as well as other protease inhibitors like pepstatin are useful for the protection of proteins during their isolation from tissues or membranes. Leupeptin can be removed from the reaction by dialysis.", "Country": "XG", "Code": "Applications", "Name": "Applications" }, { "Language": "en", "Value": "Protease inhibitor of serine and cysteine proteases.", "Country": "XG", "Code": "Positioning", "Name": "Positioning" }, { "Language": "en", "Value": "Leupeptin inhibits serine and thiol proteases such as trypsin, plasmin, proteinase K, kallikrein, papain, thrombin, and cathepsin A and B.
Not affected are α-, β-, γ- and δ- chymotrypsin, pepsin, cathepsin D, elastase, renin, and thermolysin.
Effective concentration 10-100 μM.", "Country": "XG", "Code": "Product Description", "Name": "Product Description" }, { "Language": "en", "Value": "Formula: C₂₀H₃₈N₆O₄ × ½ H₂SO₄
Molar Mass: 475.6 g/mol
Appearance: White powder
Leupeptin (HPLC): 96.5 area %
Performance test (Inhibition of Trypsin; Inhibition exists): corresponds
Stability: At +2°C to +8°C: within specification range for 12 months; stored dry.", "Country": "XG", "Code": "Specification", "Name": "Specification" }, { "Language": "en", "Value": "Biological source: Synthetic
InChI Key: CIPMKIHUGVGQTG-VFFZMTJFSA-N
Assay: ≥96.5%
Form: powder
Molecular weight: D 475.6
Solubility(in H₂O): 50 mg/mL
Storage temperature: +2 to +8°C", "Country": "XG", "Code": "Properties", "Name": "Properties" }, { "Language": "en", "Value": "Will be supplied \"Leupeptin, synthetic\". Unit of measure is \"mg\". Minimum order quantity is 1500 mg.", "Country": "XG", "Code": "CB - Order Information", "Name": "CB - Order Information" } ] } } ] }