{ "ProductData": { "RelatedLinks": "", "RegulatoryDisclaimer1": "For further processing only.", "RegulatoryDisclaimer2": "", "StainLocalization": [ "" ], "ProductType": "Others", "DisclaimerGroup2": null, "ProductNameGlobal": "Lactate 2-Monooxygenase Lactate oxidase Grade I", "DisclaimerGroup1": "Non-IVD", "ControlTissue": [ "" ], "BrandName": "Lactate 2-Monooxygenase (Lactate oxidase), Grade I", "LicenseDisclaimers": [ ], "Isotypes": "", "RegulatoryDisclaimer3": "", "ID": "3.1.1.4.28.4", "ProductNameAddition": "from Aerococcus viridans, expressed in E. coli, lyophilizate", "Species": [ "" ], "Clone": "" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxomony": { "Product2TaxomonyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Enzymes", "NodeID": "02-0014" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeName": "Oxidases", "NodeID": "70-040-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Clinical Chemistry Raw Materials", "NodeID": "02-0011" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeName": "Carbohydrate Testing", "NodeID": "01-00-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeName": "Manufacturing", "NodeID": "180-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeName": "NOT APPLICABLE", "NodeID": "999-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeName": "NOT APPLICABLE", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "04822277103", "MaterialDescription": "Lactat-OD,SQ,rec.,lyo", "RegisteredProductName": "Lactate 2-Monooxygenase (Lactate oxidase), Grade I", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Lactat-OD, SQ, rec., lyo\". Unit of measure is \"MU\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Use Lactate 2-Monooxygenase, Grade I in diagnostic tests for the determination of L-lactate.", "Name": "Applications" }, { "Language": "en", "Value": "Will be supplied as \"Lactat-OD, SQ, rec., lyo\". Unit of measure is \"MU\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Recombinant oxidoreductase that catalyzes the conversion of lactate to pyruvate.", "Name": "Positioning" }, { "Language": "en", "Value": "Nomenclature: L-lactate:oxigen oxidoreductase
CAS Number: 9028-72-2
Michaelis constant: L-lactate: 5 x 10-4 mol/L
Vmaximum: L-lactate: 0.2 mol/L
pH optimum: 6.5-7.5 (see figure)
Temperature dependence: See figure
pH stability: 6.0-9.0 (see figure)
Thermal stability: Up to +65°C (see figure)", "Name": "Properties" }, { "Language": "en", "Value": "Appearance: Yellow lyophilizate
Activity: (+25°C, L-lactate): ≥40 U/mg lyophilizate
Specific activity: ≥55 U/mg protein
Contaminants (expressed as percentage of Lactate 2-Monooxygenase activity):
Catalase: ≤0.2
Glucose oxidase: ≤0.001
Pyruvate oxidase: ≤0.001
Uricase: ≤0.001
Stability: At -15 to -25°C within specification range for 12 months. Store dry.", "Name": "Specification" } ] } } ] }

Lactate 2-Monooxygenase (Lactate oxidase), Grade I

from Aerococcus viridans, expressed in E. coli, lyophilizate

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