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Calibration: Calibrator\t\t\t\t\t\t\t Calibrator C Bio (CAL C, 484) Calibration mode\t\t\t\t Linear regression Calibration interval\t\t\t\tEach new lot, and if recalibration is required due to QC results
Quality control: Control C Level 1 Bio (CONC1, 501) Control C Level 2 Bio (CONC2, 502) Control C Level 3 Bio (CONC3, 503)
Use the recommended control material. Other suitable control material can be used in addition. Control intervals and acceptance limits should be adapted to each laboratory's individual requirements. If values do not fall within the defined limits, corrective measures and recalibration are required",
"Name": "Protocols - Help Corner"
},
{
"Language": "English",
"Value": "Due to its test design, the assay detects both Fe2+ and Fe3+ irons
The Iron assay detects all solved iron, independently of the oxidation state (Fe2+ or Fe3+). This is a requirement for the assay, because Fe2+ easily converts to Fe3+ in presence of oxygen and backwards. In a first step of the assay, Fe ions are released from complexes and Fe3+ is reduced to Fe2+. Then the total Fe2+ reacts with the chromogenic reagent for detection:
Complexed iron is liberated at pH<2, resulting in free iron ions.
Fe3+ ions are reduced by ascorbate to Fe2+
Fe2+ ions and FerroZine form a colored complex
The absorbance measured at 552nm is directly proportional to the iron concentration of the sample (Fe2+ and Fe3+ irons)
",
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"Language": "English",
"Value": "
Analyzer and accessories
Cedex Bio HT Analyzer*, including accessories and disposables
Standard laboratory equipment
Calibrators and Controls
Calibrator C Bio*
Control C Level 1 Bio*
Control C Level 2 Bio*
Control C Level 3 Bio*
",
"Name": "Additional Equipment and Reagent Required"
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{
"Language": "English",
"Value": "This product is intended for quantitative determination of iron ions in aqueous solutions using the Cedex Bio HT Analyzer.",
"Name": "Product Description"
},
{
"Language": "English",
"Value": "
Colorimetric detection with FerroZine
Complexed iron is liberated at low pH. Fe(III) ions are reduced to Fe(II) ions by ascorbate. Fe(II) ions react with FerroZine to form a colored complex. The absorbance measured at 552 nm is directly proportional to the iron concentration of the sample.
Handle all samples as if potentially infectious, using safe laboratory procedures. As the sensitivity and titer of potential pathogens in the sample material can vary, the operator must optimize pathogen inactivation and follow the appropriate measures according to local safety regulations.
Do not eat, drink, or smoke in the laboratory work area.
Do not pipette by mouth.
Wear protective disposable gloves, laboratory coats, and eye pro\u00adtection, when handling samples and kit reagents.
Wash hands thoroughly after handling samples and reagents.
Waste handling
Discard unused reagents and waste in accordance with country, federal, state, and local regulations.
Safety Data Sheets (SDS) are available online at dialog.roche.com, or upon request from the local Roche office.
",
"Name": "Content"
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"Language": "English",
"Value": "Iron is an essential trace metal required in cell cultures and microbial fermentation. For optimal cell growth and product formation the iron concentration has to be kept whithin an appropriate concentration range, providing sufficient nutrition and avoiding toxical inhibition. For control of culture media and for monitoring in a culture process, the iron concentration can be determined on a Cedex Bio or Cedex Bio HT Analyzer with high reliability and convenience.",
"Name": "Applications"
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"Language": "English",
"Value": "Method: Colorimetric detection with FerroZine. Recovery: ±10%",
"Name": "Specification"
},
{
"Language": "English",
"Value": "Measuring Range Iron concentration can be determined in following ranges:
FE2B: 0.05 - 10.0 mg/L, (0.9 - 179 μmol/L)
FE2D: 0.5 - 100.0 mg/L (9 - 1,790 μmol/L),
up to 1 g/L (17.9 mmol/L) with automatic dilution Conversion Factors Conversion factors for phosphate concentration:
1 μmol/L = 0.0559 mg/L
1 mg/L = 17.89 μmol/L
Traceability This method has been standardized against a primary standard reference material (SRM 937).
Precision Representative performance data on Cedex Bio HT Analyzers are shown. Results obtained in individual laboratories may differ. Precision was determined in samples of three concentration levels. Coefficients of variation (CV) were calculated for in-run precision (n=21) and inter-run precision (on 21 days).
Level 1
Level 2
Level 3
Mean
11.2 mmol/L (0.63 mg/L)
19.9 mmol/L (1.11 mg/L)
30.7 mmol/L (1.72 mg/L)
CV in-run
1.0%
0.9%
0.5%
CV inter-run
2.3%
1.3%
1.3%
",
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"BrandName": "Control C Level 3 Bio",
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For measurement of acute pancreatitis (pancreatic α-amylase) in human serum and urine selective blocking of salivary α-amylase isoenzyme is achieved in the presence of the pancreatic h-α-amylase.Qualified for thecobas platforms.
Product Description
For measurement of acute pancreatitis (pancreatic α-amylase) in human serum and urine selective blocking of salivary α-amylase isoenzyme is achieved in the presence of the pancreatic h-α-amylase.Qualified for thecobas platforms.
Ordering
Name
PackSizePIM360
Description
11543601103
custom fill
MAKM-Tu66C7-IgG(BR)SQ
Notes
Will be supplied as "MAK<H-S-Amy>M-Tu66C7-IgG(BR)SQ". Unit of measure is "g active ingredient".
