{ "ProductData": { "RelatedLinks": "", "RegulatoryDisclaimer1": "For further processing only.", "RegulatoryDisclaimer2": "", "StainLocalization": [ "" ], "ProductType": "Others", "DisclaimerGroup2": null, "ProductNameGlobal": "Framework IgG", "DisclaimerGroup1": "Non-IVD", "ControlTissue": [ "" ], "BrandName": "Framework IgG", "LicenseDisclaimers": [ ], "Isotypes": "", "RegulatoryDisclaimer3": "", "ID": "3.7.9.6.2.19", "ProductNameAddition": "lyophilizate", "Species": [ "" ], "Clone": "" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxomony": { "Product2TaxomonyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Interference Blocker", "NodeID": "02-0030" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeName": "Antibody interference blocker", "NodeID": "70-005-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Immunology Raw Materials", "NodeID": "02-0035" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeName": "Manufacturing", "NodeID": "180-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeName": "NOT APPLICABLE", "NodeID": "999-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeName": "NOT APPLICABLE", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "03369846103", "MaterialDescription": "Framework IEP *SQ", "RegisteredProductName": "Framework IgG", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Framework IgG *SQ\". Unit of measure is \"mg active ingredient\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Immunogen: PTH
Spleen donor: Mouse Balb/c
Antibody class: IgG1, kappa
Preparation: Framework IEP is lyophilized from a solution containing protein, potassium phosphate and NaCl. No further preservatives are added.", "Name": "Product Description" }, { "Language": "en", "Value": "Will be supplied as \"Framework IgG *SQ\". Unit of measure is \"mg active ingredient\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "The monoclonal Framework IgG eliminates monomeric (\"immuno-response\") and highly specific interferences against the framework regions of the antibodies. Its interference eliminating strength is based on identical immuno-reactive conformational epitopes in the framework region of the test antibody.", "Name": "Applications" }, { "Language": "en", "Value": "Appearance: White lyophilizate
Solubility: Clear, colorless to slightly opalescent solution in NaCl, 0.9% (c=10 mg/mL)
Purity (HPLC): ≥90% IgG of total protein
Functional activity (relative titer based on masterlot): ≥80%
Recommended working concentration: 20-5,000 μg/mL incubation buffer
pH 5.5 treatment (30 minutes): Corresponds to specification
Stability: At -15 to -25°C within specification range for 24 months. Avoid repeated freezing and thawing.", "Name": "Specification" }, { "Language": "en", "Value": "Molecular structure: IgG1, monomer
Remark: Cannot be used in test systems for determination of PTH.
Serum concentrations of CK-MM: ≤3 U/mL have shown neither influence on interference elimination properties nor on recovery of analyte.", "Name": "Properties" } ] } } ] }

Framework IgG

lyophilizate

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