For use in quality control/manufacturing process only. Others FcRn IgG Control FcRn IgG Control PID00000007 for functional control of the FcRn Affinity Column Gen 2 09 494 804 001 9 494 804 001 09494804001 9494804001 09494804001 FcRn IgG Control FcRn IgG Control 07613336207857 Reagents, kits 1 mL Not Available CustomBiotech product. Please contact your local representative. Unit of measure is one piece. Control solution for reliable and convenient quality control of the FcRn Affinity Column Gen2. en The FcRn IgG Control provides an easy and reproducible check for the column functionality. Custom preparations of IgG or albumin can be used for additional control. en Volume: 0.2 mL concentrate, to be reconstituted to 1 mL control solution, sufficient for ≥ 30 test runs within the stability periodTest result: Chromatography on the FcRn Affinity Column Gen2 results in 3 distinguishable peaks. en The FcRn Affinity Column Gen2 is designed for chromatographic differentiation of structural variants of monoclonal IgG. The FcRn IgG Control contains structural variants of an IgG and is used to check the separation capacity of the column. After >100 runs or after inappropriate handling of the column, for example, by exposure to aggressive reagents, the separation capacity may be reduced and may no longer be acceptable. Therefore, the FcRn IgG Control is a convenient and reproducible funtional control of the column performance in quality control and troubleshooting. en The FcRn IgG Control contains a preparation of an IgG that was partially oxidized to produce two structure variants, which can be separated and detected using the FcRn Affinity Column Gen2. If a column is no longer able to show a clear separation of these variants, then its functional performance may no longer be acceptable.For more detailed background information about the different structures of the variants and their preparation, see the publication: Stracke J, et al, 2014. en

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FcRn IgG Control

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