{ "ProductData": { "ID": "3.6.5.1.16.1", "ProductType": "Others", "BrandName": "dUTP, PCR Grade", "ProductNameAddition": "sodium salt, 100 mM", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": null, "DisclaimerGroup2": null, "RegulatoryDisclaimer3": null, "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "dUTP PCR Grade sodium salt 100 mM" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE_.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0018", "StructureNodeStatus": "valid", "NodeName": "Nucleotides" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeID": "70-015-00", "StructureNodeStatus": "valid", "NodeName": "Deoxyucleotides" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeID": "01-01-01-07-00", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0136", "StructureNodeStatus": "valid", "NodeName": "Molecular Raw Materials" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeID": "210-00", "StructureNodeStatus": "valid", "NodeName": "PCR/qPCR" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeID": "300-00", "StructureNodeStatus": "valid", "NodeName": "RT-PCR/qRT-PCR" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeID": "520", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeID": "180-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeID": "999", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "11889532103", "MaterialDescription": "dUTP,Na, Solution (PCR Grade)", "RegisteredProductName": "dUTP, PCR Grade", "GTIN": "07613336131541", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "100 mL", "PackSizeDescPIM360": "10,000 μmol", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as ''dUTP, Na, Solution (PCR Grade)''. Unit of measure is ''μmol''." }, { "MaterialNum": "04631145103", "MaterialDescription": "dUTP PCR Grade, Sodium Solution, 20 ml", "RegisteredProductName": "dUTP, PCR Grade", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "20 mL", "PackSizeDescPIM360": "2,000 μmol", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as ''dUTP PCR Grade, Sodium Solution, 20 mL''. Unit of measure is ''μmol''." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Name": "Applications", "Value": "dUTP, PCR Grade, is designed for amplification reactions where high-quality reagents are required, such as for in vitro diagnostics. Avoid DNA carryover contamination between PCRs that can be a source of false positives.
To decontaminate PCR and RT-PCR mixes, dUTP is incorporated in place of dTTP into the PCR product. Reaction mixes are then pre-treated with Uracil-DNA Glycosylase (UNG) before amplification to degrade contaminating dUTP-containing PCR products.", "Language": "en", "Country": "XG", "Code": "Applications" }, { "Name": "Product Description", "Value": "dUTP, PGR Grade, is supplied in sealed and CO₂-proof bottles to ensure a stable pH during shipment on dry ice. The manufacturing process is fully validated including the final filling step. The pH is adjusted to match conditions for amplification.", "Language": "en", "Country": "XG", "Code": "Product Description" }, { "Name": "Quality Control", "Value": "Manufactured under GMP (Good Manufacturing Practice) regulations.", "Language": "en", "Country": "XG", "Code": "Quality Control" }, { "Name": "CB - Order Information", "Value": "11889532103: Will be supplied as ''dUTP, Na, Solution (PCR Grade)''. Unit of measure is ''μmol''.
04631145103: Will be supplied as ''dUTP PCR Grade, Sodium Solution, 20 mL''. Unit of measure is ''μmol''.", "Language": "en", "Country": "XG", "Code": "CB - Order Information" }, { "Name": "Positioning", "Value": "GMP-manufactured dNTPs from the leading manufacturer of nucleotides for outstanding, consistent performance in amplification reactions.", "Language": "en", "Country": "XG", "Code": "Positioning" }, { "Name": "Specification", "Value": "Appearance: Clear, colorless solution
pH value: 8.1-8.5
dUTP (1 μmol ≙ 9.9 A₂₆₀ units, pH 7.0): 100-110 mmol/L
dUTP (high resolution HPLC method): ≥99 area%
dUDP (HPLC): ≤0.9 area%
DNases/RNases: Negative
Nicking activity: Negative
A₂₅₀/A₂₆₀: 0.74±0.02
A₂₈₀/A₂₆₀: 0.38±0.02
A₂₉₀/A₂₆₀: 0.04±0.01
Function test in RT-PCR (RNA, human dystrophin, and mouse β-actin gene): Corresponds to specification
Stability: At -15 to -25°C within specification range for 42 months.", "Language": "en", "Country": "XG", "Code": "Specification" }, { "Name": "Properties", "Value": "Nomenclature: 2'-Deoxy-uridine-5'-triphosphate
CAS Number: 94736-09-1
Formula: C₉H₁₅N₂O₁₄P₃
Molecular weight: 468.2 D", "Language": "en", "Country": "XG", "Code": "Properties" } ] } } ] }