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CAS Number: 9028-36-8
Michaelis constants (Tris maleate buffer, pH 8.0, +25°C):
D-lactate: 0.7 x 10-1 mol/L (NAD, 2 mmol/L)
Pyruvate: 1.2 x 10-3 mol/L (NADH, 0.1 mmol/L)
NADH: 7.1 x 10-5 mol/L (pyruvate, 20 mmol/L)
pH optimum: 7.0
pH stability: 4.0-10.0
Thermal stability: Up to +50°C
Specificity: Lactate dehydrogenase is specific for D(-)-lactate, L(+)-lactate does not react.", "Name": "Properties" }, { "Language": "en", "Value": "Appearance: White to yellowish lyophilizate
Solubility: Clear, colorless to slightly yellowish solution in water (c=10 mg/mL)
pH value (c=10 mg/mL in water): 5.7-6.7
Activity (+25°C, pyruvate): ≥150 U/mg lyophilizate
Specific activity: ≥300 U/mg protein
Protein (Biuret): No limit, approximately 0.4-0.7 mg/mg lyophilizate
Contaminants (expressed as percentage of D-Lactate Dehydrogenase activity):
Alcohol dehydrogenase: ≤0.01
GIucose dehydrogenase: ≤0.01
Malate dehydrogenase: ≤0.1
Succinate dehydrogenase: ≤0.01
Stability: At +2 to +8°C within specification range for 12 months. Store dry.", "Name": "Specification" } ] } } ] }

D-Lactate Dehydrogenase (D-LDH), Grade II

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