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"IdentifierofStructureSystem": "OWP_Organization", "NameofStructureSystem": "Organization", "StructureNodeID": "01-01-01-07-00", "StructureGroupPath": "Roche Diagnostics Solution (RDS)->Customer Areas->Core lab->CustomBiotech and LifeScience", "StructureGroupName": "CustomBiotech and LifeScience" }, { "IdentifierofStructureSystem": "OWP_Techniques", "NameofStructureSystem": "Techniques", "StructureNodeID": "300-00", "StructureGroupPath": "RT-PCR/qRT-PCR", "StructureGroupName": "RT-PCR/qRT-PCR" }, { "IdentifierofStructureSystem": "Product_Solutions", "NameofStructureSystem": "Product Solutions", "StructureNodeID": "520", "StructureGroupPath": "CustomBiotech", "StructureGroupName": "CustomBiotech" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "180-00", "StructureGroupPath": "Manufacturing", "StructureGroupName": "Manufacturing" }, { "IdentifierofStructureSystem": "Applications", "NameofStructureSystem": "Applications", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Disease_Areas", "NameofStructureSystem": "Disease Areas", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Pathogens", "NameofStructureSystem": "Pathogens", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "999", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Product_Grouping", "NameofStructureSystem": "Product Grouping", "StructureNodeID": "02-0090", "StructureGroupPath": "CustomBiotech->Vaccine Testing", "StructureGroupName": "Vaccine Testing" } ] } ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Together with ATP, GTP, UTP and/or modified UTP, CTP is part of the ribonucleotide mix needed to synthesize mRNA in the presence of a RNA polymerase.", "Name": "Applications" }, { "Language": "en", "Value": "CTP is produced enzymatically, a virus filtration concludes the synthesis, a TSE/BSE statement is available. To comply with regulatory requirements, it produced under GMP, the manufacturing process is fully validated including the final filling step, followed by QC-release testing. The pH is adjusted to match conditions for in vitro transcription, the solution is supplied in sealed and CO₂-proof bottles to ensure a stable pH during shipment on dry ice.", "Name": "Product Description" }, { "Language": "en", "Value": "Will be supplied as \"CTP GMP Grade, 100 mmol/L, 100 mL\". Unit of measure is \"mL\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Manufactured under GMP (Good Manufacturing Practice) regulations.", "Name": "Quality Control" }, { "Language": "en", "Value": "Avoid to change reagents or supplier when using this NTP GMP Grade from R&D to commercialization phase, allowing a smooth transition from lab scale to industrial production scale.", "Name": "Benefits" }, { "Language": "en", "Value": "NTPs are the critical starting materials of in vitro mRNA synthesis for therapeutics or vaccines.", "Name": "Positioning" }, { "Language": "en", "Value": "Appearance: Clear, colorless solution
pH value: 8.1-8.5
CTP (A₂₆₀, pH 7.0 ε = 7.4 [L x mmol^-1 x cm^-1]): 100-110 mmol/L
CTP (HPLC): ≥98 area%
CDP (HPLC): ≤1.5 area%
CMP (HPLC): ≤0.5 area%
Qualification for molecular biology: Corresponds to specification
DNases/RNases: Negative
Nicking activity: Negative
Functional transcription assay: Corresponds to specification
Stability: At -15 to -25°C within specification range for 30 months from date of manufacture.", "Name": "Specification" }, { "Language": "en", "Value": "Nomenclature: Cytidine-5'-triphosphate
CAS Number: 65-47-4 (free acid)
Formula: C₉H₁₆N₃O₁₄P₃ (free acid)​​​​​​​
Molecular weight: 483.2 D (free acid)", "Name": "Properties" } ] } } ] }