{ "ProductData": { "RelatedLinks": "", "RegulatoryDisclaimer1": "For further processing only.", "RegulatoryDisclaimer2": "", "StainLocalization": [ "" ], "ProductType": "Others", "DisclaimerGroup2": null, "ProductNameGlobal": "CTP GMP Grade", "DisclaimerGroup1": "Non-IVD", "ControlTissue": [ "" ], "BrandName": "CTP, GMP Grade", "LicenseDisclaimers": [ ], "Isotypes": "", "RegulatoryDisclaimer3": "", "ID": "3.6.5.5.1.2", "ProductNameAddition": "sodium salt, 100 mM", "Species": [ "" ], "Clone": "" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxomony": { "Product2TaxomonyReferences": [ { "StructureSystemIdentifier": "OWP_Product_Solutions", "StructureSystemName": "OWP Product Solutions", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "CustomBiotech->Nucleotides", "NodeID": "02-0018" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "CustomBiotech->mRNA Reagents", "NodeID": "02-0062" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "OWP Product Types", "NodeName": "Raw Materials->Ribonucleotides", "NodeID": "70-048-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "OWP Organization", "NodeName": "Roche Diagnostics Solution (RDS)->Customer Areas->Core lab->CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "OWP Techniques", "NodeName": "RT-PCR/qRT-PCR", "NodeID": "300-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeName": "CustomBiotech", "NodeID": "520" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "04980875103", "MaterialDescription": "CTP Mol Dia Grade, 100 mmol/l, 100 ml", "RegisteredProductName": "CTP, GMP Grade", "GTIN": "07613336131350", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "100 mL", "PackSizeDescPIM360": "10 mmol", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"CTP Mol Dia Grade, 100 mmol/L, 100 mL\". Unit of measure is \"mL\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "CTP, GMP Grade, is designed for in vitro transcription reactions and alternative amplification reactions where high-quality reagents are required, such as for the manufacture of in vitro diagnostics, or mRNA therapeutics.", "Name": "Applications" }, { "Language": "en", "Value": "CTP, GMP Grade, is supplied in sealed and CO₂-proof bottles to ensure a stable pH during shipment on dry ice. The manufacturing process is fully validated including the final filling step. The pH is adjusted to match conditions for reverse transcription and amplification.", "Name": "Product Description" }, { "Language": "en", "Value": "Will be supplied as \"CTP GMP Grade, 100 mmol/L, 100 mL\". Unit of measure is \"mL\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Manufactured under GMP (Good Manufacturing Practice) regulations.", "Name": "Quality Control" }, { "Language": "en", "Value": "Use ribonucleotides from one of the leading manufacturer of nucleotides for outstanding, consistent performance in transcription reactions, from small to large scales.
Reduce efforts and risks by using GMP-manufactured ribonucleotides in development and manufacturing of mRNA therapeutics.", "Name": "Benefits" }, { "Language": "en", "Value": "GMP-manufactured ribonucleotides from the leading manufacturer of nucleotides for outstanding, consistent performance in amplification reactions.", "Name": "Positioning" }, { "Language": "en", "Value": "Appearance: Clear, colorless solution
pH value: 8.1-8.5
CTP (A₂₆₀, pH 7.0 ε = 7.4 [L x mmol^-1 x cm^-1]): 100-110 mmol/L
CTP (HPLC): ≥98 area%
CDP (HPLC): ≤1.5 area%
CMP (HPLC): ≤0.5 area%
Qualification for molecular biology: Corresponds to specification
DNases/RNases: Negative
Nicking activity: Negative
Functional transcription assay: Corresponds to specification
Stability: At -15 to -25°C within specification range for 30 months.", "Name": "Specification" }, { "Language": "en", "Value": "Nomenclature: Cytidine-5'-triphosphate
CAS Number: 18423-42-2
Formula: C₉H₁₆N₃O₁₄P₃
Molecular weight: 483.2 D", "Name": "Properties" } ] } } ] }