{ "ProductData": { "RelatedLinks": "", "RegulatoryDisclaimer1": "For further processing only.", "RegulatoryDisclaimer2": "", "StainLocalization": [ "" ], "ProductType": "Others", "DisclaimerGroup2": null, "ProductNameGlobal": "Creatinase", "DisclaimerGroup1": "Non-IVD", "ControlTissue": [ "" ], "BrandName": "Creatinase", "LicenseDisclaimers": [ ], "Isotypes": "", "RegulatoryDisclaimer3": "", "ID": "3.1.3.3.17.3", "ProductNameAddition": "from microorganism, lyophilizate", "Species": [ "" ], "Clone": "" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxomony": { "Product2TaxomonyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Enzymes", "NodeID": "02-0014" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeName": "Hydrolases", "NodeID": "70-023-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Clinical Chemistry Raw Materials", "NodeID": "02-0011" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeName": "Nitrogen Metabolism Testing", "NodeID": "16-00-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeName": "Manufacturing", "NodeID": "180-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeName": "NOT APPLICABLE", "NodeID": "999-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeName": "NOT APPLICABLE", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "11799142103", "MaterialDescription": "Creatinase, Microbial Lyophil.Substance", "RegisteredProductName": "Creatinase", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Creatinase, Microbial Lyophil. Substance\". Unit of measure is \"MU\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Use Creatinase in your diagnostic tests for the determination of creatinine in combination with Creatininase, Catalog No. 11 865 471 103 and Sarcosine Oxidase, Catalog No. 11 378 856 103.", "Name": "Applications" }, { "Language": "en", "Value": "Will be supplied as \"Creatinase, Microbial Lyophil. Substance\". Unit of measure is \"MU\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Hydrolase for creatinine determination that catalyzes the conversion of creatine to sarcosine and urea.", "Name": "Positioning" }, { "Language": "en", "Value": "CAS Number: 37340-58-2", "Name": "Properties" }, { "Language": "en", "Value": "Appearance: White to slightly yellowish lyophilizate
Solubility: Clear, colorless solution in water (c=10 mg/mL)
pH value (c=10 mg/mL in water): 5.5-6.5
Activity (+25°C, creatine, POD/PAP method): ≥4 U/mg lyophilizate
Specific activity: ≥9 U/mg protein
Protein (Biuret): 0.3-0.5 mg/mg lyophilizate
Contaminants (expressed as percentage of Creatinase activity):
Creatininase: ≤0.01
Catalase: ≤2
Creatinine deaminase: ≤0.01
Proteases (casein/resorufin, 2 hours stress duration): ≤0.001
Contaminating oxidases (FOX): ≤0.001
Stability: At -15 to -25°C within specification range for 12 months.", "Name": "Specification" } ] } } ] }

Creatinase

from microorganism, lyophilizate

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