{ "ProductData": { "ID": "3.5.3.3.4.5", "ProductType": "Others", "BrandName": "Collagenase P", "ProductNameAddition": "from Clostridium histolyticum", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": null, "DisclaimerGroup2": null, "RegulatoryDisclaimer3": null, "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "Collagenase P from Clostridium histolyticum" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE_.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeID": "70-044-00", "StructureNodeStatus": "valid", "NodeName": "Proteases" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeID": "01-01-01-07-00", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeID": "330-00", "StructureNodeStatus": "valid", "NodeName": "Tissue Dissociation" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeID": "520", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeID": "180-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeID": "999", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeID": "99-00-00", "StructureNodeStatus": "invalid", "NodeName": "" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0133", "StructureNodeStatus": "valid", "NodeName": "Cell and Gene Therapy" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0112", "StructureNodeStatus": "valid", "NodeName": "Protease Portfolio" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0014", "StructureNodeStatus": "valid", "NodeName": "Enzymes" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeID": "02-0008", "StructureNodeStatus": "valid", "NodeName": "Biologics" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "11215809103", "MaterialDescription": "Collagenase P from Clostridium histoly.", "RegisteredProductName": "Collagenase P", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Collagenase P from Clostridium histoly.\". Unit of measure is \"G\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Name": "Applications", "Value": "Collagenase from C. histolyticum is used for the dissociation of tissues for the establishment of primary cell cultures. Because of its high collagenase activity Collagenase P is particularly suitable for the isolation of pancreatic islets from mouse and rat (function tested). The preparation is also suitable for the isolation of adipocytes from epididymal fat pads of rats.", "Language": "en", "Country": "XG", "Code": "Applications" }, { "Name": "CB - Order Information", "Value": "Will be supplied as \"Collagenase P from Clostridium histoly.\". Unit of measure is \"G\".", "Language": "en", "Country": "XG", "Code": "CB - Order Information" }, { "Name": "Product Description", "Value": "The product is prepared from the extracellular culture filtrate of a special Clostridium histolyticum strain.", "Language": "en", "Country": "XG", "Code": "Product Description" }, { "Name": "Specification", "Value": "Appearance: Light brown to brown lyophilized substance
Activity (+25°C; with PZ-Pro-Leu-Gly-Pro-D-Arg ): ≥1.5 U/mg, lyophilized material

Contaminants expressed as percentage of collagenase P activity:
Clostripain: no limit (U/mg lyophilized material)
Proteases (azocoll): no limit (U/mg lyophilized material)
Trypsin (with BAEE): no limit (U/mg lyophilized material)
Performance test with pancreatic cells: corresponds
Stability: At + 2°C to + 8°C: within specification range for 12 months; stored dry and protected from light.", "Language": "en", "Country": "XG", "Code": "Specification" } ] } } ] }