{ "ProductData": { "RelatedLinks": "", "RegulatoryDisclaimer1": "For further processing only.", "RegulatoryDisclaimer2": "", "StainLocalization": [ "" ], "ProductType": "Others", "DisclaimerGroup2": null, "ProductNameGlobal": "Collagenase P from Clostridium histolyticum", "DisclaimerGroup1": "Non-IVD", "ControlTissue": [ "" ], "BrandName": "Collagenase P", "LicenseDisclaimers": [ ], "Isotypes": "", "RegulatoryDisclaimer3": "", "ID": "3.5.3.3.4.5", "ProductNameAddition": "from Clostridium histolyticum", "Species": [ "" ], "Clone": "" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxomony": { "Product2TaxomonyReferences": [ { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeName": "Proteases", "NodeID": "70-044-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Protease Portfolio", "NodeID": "02-0112" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Enzymes", "NodeID": "02-0014" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeName": "Tissue Dissociation", "NodeID": "330-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeName": "Manufacturing", "NodeID": "180-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeName": "NOT APPLICABLE", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Biologics", "NodeID": "02-0008" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "11215809103", "MaterialDescription": "Collagenase P from Clostridium histoly.", "RegisteredProductName": "Collagenase P", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Collagenase P from Clostridium histoly.\". Unit of measure is \"G\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Collagenase from C. histolyticum is used for the dissociation of tissues for the establishment of primary cell cultures. Because of its high collagenase activity Collagenase P is particularly suitable for the isolation of pancreatic islets from mouse and rat (function tested). The preparation is also suitable for the isolation of adipocytes from epididymal fat pads of rats.", "Name": "Applications" }, { "Language": "en", "Value": "Will be supplied as \"Collagenase P from Clostridium histoly.\". Unit of measure is \"G\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "The product is prepared from the extracellular culture filtrate of a special Clostridium histolyticum strain.", "Name": "Product Description" }, { "Language": "en", "Value": "Appearance: Light brown to brown lyophilized substance
Activity (+25°C; with PZ-Pro-Leu-Gly-Pro-D-Arg ): ≥1.5 U/mg, lyophilized material

Contaminants expressed as percentage of collagenase P activity:
Clostripain: no limit (U/mg lyophilized material)
Proteases (azocoll): no limit (U/mg lyophilized material)
Trypsin (with BAEE): no limit (U/mg lyophilized material)
Performance test with pancreatic cells: corresponds
Stability: At + 2°C to + 8°C: within specification range for 12 months; stored dry and protected from light.", "Name": "Specification" } ] } } ] }

Collagenase P

from Clostridium histolyticum

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