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For further processing only. Others Collagenase I GMP Grade Collagenase I, GMP Grade 3.5.3.3.4.6 liquid, mammalian free, from Chlostridium histolyticum 05 172 969 103 5 172 969 103 05172969103 5172969103 05172969103 Collagenase I, liquid, mammalian free Collagenase I, GMP Grade 07613336131169 Reagents, kits custom fill Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "Collagenase I, liquid, mammalian free". Unit of measure is "G". 9001-12-1 en Collagenase I, GMP Grade is a specialized liquid enzyme produced from Clostridium histolyticum for critical bioprocessing and cell therapy applications. Formulated completely free of mammalian- or avian-derived raw materials, this enzyme specifically targets native collagen while keeping non-target cell surface structures intact.With high total purity, controlled side activities, and low endotoxin levels, Collagenase I ensures reliable batch-to-batch consistency and seamless integration into automated or manual workflows. en Composition: HEPES, 5 mmol/l; CaCl2, 1 mmol/l; pH approx. 7.5Specific activity (Wünsch): 0.10 – 0.60 U/mg proteinClostripain (BAEE): ≤0.5U/mg proteinTrypsin (Chromozym): ≤0.5 U/mg proteinTarget protein concentration: 55 mg/mlHPLC purity total: ≥90 area-%HPLC contamination with Collagenase II: ≤3 %Endotoxin: ≤50 EU/mg proteinTotal bacterial count: ≤100 CFU/mlStability at -25°C to -15°C: within specification range for 24 months. en Highly purified, mammalian-free liquid enzyme engineered to provide high cell yield, high viability, and reproducible tissue dissociation for bioprocessing and cell therapy manufacturing. en Primary cell isolation: Dissociation of collagen-dense extracellular matrices (ECMs) for high-recovery isolation of viable primary cells.Cell and gene therapy manufacturing: Reliable tissue digestion step integrated into regulated commercial bioprocesses and advanced therapies.Custom enzyme formulation: Blending with Collagenase II and secondary proteases (such as neutral proteases) to optimize digestion protocols for specific tissue types. en