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Unit of measure is \"kg\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Benefits of using in vitro glycoengineering to modify glycosylation of therapeutic proteins:
  • Time- and cost-saving generation of glycan variants to develop improved drugs
  • Optimized glycosylation without compromising other CQAs or product yield
  • Improved lot-to-lot consistency to reduce risk of product quality variation and resulting delays
  • Generation of glycoprofiles which may not otherwise be generated
  • Streamlined analytics in comparability studies
", "Name": "Benefits" }, { "Language": "en", "Value": "CMP-N-Acetylneuraminic Acid is an activated sugar, and can be used for in vitro glycoengineering of glycoproteins, e.g. therapeutic proteins.", "Name": "Positioning" }, { "Language": "en", "Value": "CAS Number: 1007117-62-5
Molar mass: 659.39 g/mol
On request, product can be provided free of animal-derived components and in GMP Grade.", "Name": "Properties" }, { "Language": "en", "Value": "Appearance: White, lyophilized substance
Solution (c = 100 mg/mL water): Clear, colorless
CMP-NANA-Na2 (A260 ε=7.4 [L x mmol-1 x cm-1]): ≥87%
CMP-NANA (HPLC): ≥90 area%
CMP-NANA + CMP (HPLC): ≥95 area%
Na (flame photometric): 6-8%
Water (K. Fischer): ≤8%
Heavy metals (as Pb): ≤25 ppm (in validation)
CMP (HPLC): ≤10 area%
CDP (HPLC): ≤1 area%
CTP (HPLC): ≤0.5 area%
Sialic acid (free and dehydrated): ≤10 area%
Sum of unknown impurities (HPLC): ≤1 area%
Bioburden: ≤100 CFU/g
Stability: At -15 to -25°C within specification range for 24 months.", "Name": "Specification" } ] } } ] }

CMP-N-Acetylneuraminic Acid (CMP-NANA)

sodium salt, lyophilizate

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