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For further processing only. Others Catalase solution Catalase 3.1.5.4.13.13 from Corynebacterium glutamicum, solution 11 668 153 103 11668153103 Catalase Microbial in Glycerol Catalase Reagents, kits custom fill Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "Catalase Microbial in Glycerol". Unit of measure is "GU". EC 1.11.1.6 en 9001-05-2 en For formulators and R&D teams in the ophthalmic industry, catalase is a crucial biocatalyst employed in two-step hydrogen peroxide disinfection systems for contact lenses. The enzyme's primary function is the rapid and controlled neutralization of the 3% hydrogen peroxide (H2O2) solution, which, while an effective broad-spectrum antimicrobial agent, is cytotoxic and a significant corneal irritant.
Catalase is typically integrated into the system using two common delivery mechanisms:
1) Immobilized enzyme: Coated onto a solid-state catalytic disc (often platinum-based) fixed within the lens case.
2) Solid-Dose Formulation: Delivered as a tablet that dissolves to release the enzyme.
The enzyme efficiently catalyzes the decomposition of hydrogen peroxide (2H2O2 --> 2H2O+ O2), rapidly reducing residual H2O2 concentrations to physiologically safe, non-irritating levels (e.g., <100 ppm).
This bioconversion transforms the sterilizing solution into a sterile, isotonic, and biocompatible saline buffer, ensuring the lens is safe for ocular insertion after the defined disinfection and neutralization cycle. en Biological activity: 150 IU of Catalase are sufficient to completely remove 3% hydrogen peroxide in 10 minutes.Source: Microbial from Corynebacterium glutamicum en Catalase functions as a specific biocatalyst to neutralize hydrogen peroxide by decomposing it into water and oxygen, supporting applications in industrial processing, diagnostics, and research. en Appearance: Brownish-green, clear solution pH value: 7.0-8.0 Density (according to DAB 10): No limit Activity (+25°C, H2O2): ≥500,000 U/mL Glycerol (enzymatically): 310-430 mg/mL (≙ 25-35%, v/v) Ethanol (enzymatically): 71-87 mg/mL (≙ 9-11%, v/v) Water (calculated): No limit Purity (HPLC, TSK 3000, A280): ≥90 area% Bioburden: Total amount: ≤15 CFU/mL Germ differentiation according to Ph. Eur. 2.6.13 (E. coli, Salmonellae, Staphylococcus aureus, Pseudomonas aeruginosa): Below the limit of detection Stability: At +2 to +8°C within specification range for 18 months. en