For further processing only. Others Carboxypeptidase B rec from rat pancreas expressed in Pichia pastoris solution Carboxypeptidase B, rec., GMP Grade 3.1.3.2.3.2 from rat pancreas, expressed in Pichia pastoris, solution 03 358 682 103 3 358 682 103 03358682103 3358682103 03358682103 CpB rec. Carboxypeptidase B, recombinant 07613336131336 Reagents, kits 0.03 MU Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "CpB rec.". Unit of measure is "MU". EC 3.4.17.2 en 9025-24-5 en Carboxypeptidase B is a widely used metalloprotease, typically isolated from pancreas of different animals, that specifically releases arginine and lysine from the C-terminus of peptides and proteins. Roche has chemically synthesized a gene encoding for the amino acid sequence of the rat Carboxypeptidase B and has transformed the gene into the expression host Pichia pastoris, which expresses the recombinant Carboxypeptidase B as active protease with identical properties compared to the native Carboxypeptidase B.The production process is validated resulting in a very high lot-to-lot consistency. en Use the animal component-free and DIN EN ISO 13485-manufactured Carboxypeptidase B, recombinant, as critical raw material for the production of active pharmaceutical ingredients (API), i.e., insulin. en Minimize the risk of virus contamination and the risk of animalrelated cross-contamination. Rely on high purity. Minimize the risk of host cell protein contamination in your final product. Increase the safety of your production processes with robust and reproducible performance and high lot-to-lot consistency. en Appearance: Clear, colorless to slightly yellowish solution Storage buffer: Tris/HCl, 33 mmol/L; ZnCl2, 0.1 mmol/L pH (at +25°C): 7.5-8.5 Activity (with hippurylarginine): ≥400 U/mL Total activity: 30 kU ±15% Specific activity: ≥210 U/mg Protein: 2.8±0.5 mg/mL Purity (RP-HPLC): ≥85% according to master lot Bioburden: ≤50 CFU/mL Trypsin (with chromozym): ≤0.005% Shipping conditions: Dry ice Stability: At -15 to -25°C within specification range for 12 months. en

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Carboxypeptidase B, rec., GMP Grade

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