{
"ProductData": {
"ID": "3.1.1.2.13.4",
"ProductType": "Others",
"BrandName": "β-1,4-Galactosyltransferase, rec. EQ",
"ProductNameAddition": "human, expressed in CHO-K1 cells",
"RegulatoryDisclaimer1": "For further processing only.",
"DisclaimerGroup1": "",
"RegulatoryDisclaimer2": null,
"DisclaimerGroup2": null,
"RegulatoryDisclaimer3": null,
"SampleType": [
],
"LicenseDisclaimers": [
{
"Order": "78",
"Identifier": "1403506419168",
"LongText": "The sale of the Product does not exhaust or grant any rights in third party patents including patents of companies of the F. Hoffmann - La Roche AG group of companies, in particular, for the use of modified antibodies obtained by using the product."
}
],
"RelatedLinks": "",
"Clone": "",
"ControlTissue": [
""
],
"ISOtypes": "",
"Species": [
""
],
"StainLocalization": [
""
],
"ProductNameGlobal": "beta-1 4-Galactosyltransferase rec. EQ"
},
"ProductImageDetails": {
"ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png",
"ImageType": "Image main"
},
"Product2Taxonomy": {
"Product2TaxonomyReferences": [
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"StructureNodeStatus": "valid",
"NodeName": "In vitro Glycoengineering",
"NodeID": "02-0052"
},
{
"StructureSystemIdentifier": "OWP_Product_Types",
"StructureSystemName": "Product Types",
"StructureNodeStatus": "valid",
"NodeName": "Glycosyltransferases",
"NodeID": "70-025-00"
},
{
"StructureSystemIdentifier": "OWP_Organization",
"StructureSystemName": "Organization",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech and LifeScience",
"NodeID": "01-01-01-07-00"
},
{
"StructureSystemIdentifier": "Product_Grouping",
"StructureSystemName": "Product Grouping",
"StructureNodeStatus": "valid",
"NodeName": "Enzymes",
"NodeID": "02-0014"
},
{
"StructureSystemIdentifier": "Product_Solutions",
"StructureSystemName": "Product Solutions",
"StructureNodeStatus": "valid",
"NodeName": "CustomBiotech",
"NodeID": "520"
},
{
"StructureSystemIdentifier": "Lab_Type",
"StructureSystemName": "Lab Types",
"StructureNodeStatus": "invalid",
"NodeName": "",
"NodeID": "180-00"
},
{
"StructureSystemIdentifier": "Applications",
"StructureSystemName": "Applications",
"StructureNodeStatus": "invalid",
"NodeName": "",
"NodeID": "99-00-00"
},
{
"StructureSystemIdentifier": "OWP_Techniques",
"StructureSystemName": "Techniques",
"StructureNodeStatus": "invalid",
"NodeName": "",
"NodeID": "999-00"
},
{
"StructureSystemIdentifier": "Disease_Areas",
"StructureSystemName": "Disease Areas",
"StructureNodeStatus": "invalid",
"NodeName": "",
"NodeID": "99-00-00"
},
{
"StructureSystemIdentifier": "Pathogens",
"StructureSystemName": "Pathogens",
"StructureNodeStatus": "invalid",
"NodeName": "",
"NodeID": "99-00-00"
},
{
"StructureSystemIdentifier": "OWP_Family",
"StructureSystemName": "Product Families",
"StructureNodeStatus": "invalid",
"NodeName": "",
"NodeID": "999"
},
{
"StructureSystemIdentifier": "Health_Topics",
"StructureSystemName": "Health Topics",
"StructureNodeStatus": "invalid",
"NodeName": "",
"NodeID": "99-00-00"
}
]
},
"Product2Materials": {
"P2MaterialReferences": [
{
"MaterialNum": "08098182101",
"MaterialDescription": "beta-1,4-Galactosyltransferase, rec.EQ",
"RegisteredProductName": "beta-1,4-Galactosyltransferase, rec. EQ",
"GTIN": "",
"ProductCategoryText": "Reagents, kits",
"OldMaterialNumber": "",
"PackSizePIM360": "1.5 mg",
"PackSizeDescPIM360": "Not Available",
"MaterialAnnotation": "CustomBiotech product. Please contact your
local representative.",
"ReadyForUse": "",
"OrderInformation": "Unit of measure is \"piece\"."
},
{
"MaterialNum": "08098182103",
"MaterialDescription": "beta-1,4-Galactosyltransferase, rec. EQ",
"RegisteredProductName": "beta-1,4-Galactosyltransferase, rec. EQ",
"GTIN": "",
"ProductCategoryText": "Reagents, kits",
"OldMaterialNumber": "",
"PackSizePIM360": "0.4 g",
"PackSizeDescPIM360": "Not Available",
"MaterialAnnotation": "CustomBiotech product. Please contact your
local representative.",
"ReadyForUse": "",
"OrderInformation": "Unit of measure is \"gram\"."
}
]
},
"Product2Products": {
"Product2ProductReference": [
{
"ProductID": "3.1.1.2.13.3",
"BrandName": "α-2,6-Sialyltransferase, rec. EQ",
"ProductNameAddition": "human, expressed in CHO-K1 cells",
"ReferenceType": "Reagent",
"Classification": [
{
"IdentifierofStructureSystem": "Product_Grouping",
"NameofStructureSystem": "Product Grouping",
"StructureNodeID": "02-0052",
"StructureGroupPath": "CustomBiotech->In vitro Glycoengineering",
"StructureGroupName": "In vitro Glycoengineering",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "OWP_Product_Types",
"NameofStructureSystem": "Product Types",
"StructureNodeID": "70-025-00",
"StructureGroupPath": "Raw Materials->Glycosyltransferases",
"StructureGroupName": "Glycosyltransferases",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "OWP_Organization",
"NameofStructureSystem": "Organization",
"StructureNodeID": "01-01-01-07-00",
"StructureGroupPath": "Roche Diagnostics Solution (RDS)->Customer Areas->Core lab->CustomBiotech and LifeScience",
"StructureGroupName": "CustomBiotech and LifeScience",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Product_Grouping",
"NameofStructureSystem": "Product Grouping",
"StructureNodeID": "02-0014",
"StructureGroupPath": "CustomBiotech->Enzymes",
"StructureGroupName": "Enzymes",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Product_Solutions",
"NameofStructureSystem": "Product Solutions",
"StructureNodeID": "520",
"StructureGroupPath": "CustomBiotech",
"StructureGroupName": "CustomBiotech",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Lab_Type",
"NameofStructureSystem": "Lab Types",
"StructureNodeID": "180-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Applications",
"NameofStructureSystem": "Applications",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "OWP_Techniques",
"NameofStructureSystem": "Techniques",
"StructureNodeID": "999-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Disease_Areas",
"NameofStructureSystem": "Disease Areas",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Pathogens",
"NameofStructureSystem": "Pathogens",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "OWP_Family",
"NameofStructureSystem": "Product Families",
"StructureNodeID": "999",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Health_Topics",
"NameofStructureSystem": "Health Topics",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
}
]
},
{
"ProductID": "3.1.1.2.13.1",
"BrandName": "α-2,3-Sialyltransferase, rec.",
"ProductNameAddition": "human, expressed in HEK-293F, solution",
"ReferenceType": "Reagent",
"Classification": [
{
"IdentifierofStructureSystem": "Product_Grouping",
"NameofStructureSystem": "Product Grouping",
"StructureNodeID": "02-0052",
"StructureGroupPath": "CustomBiotech->In vitro Glycoengineering",
"StructureGroupName": "In vitro Glycoengineering",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "OWP_Product_Types",
"NameofStructureSystem": "Product Types",
"StructureNodeID": "70-025-00",
"StructureGroupPath": "Raw Materials->Glycosyltransferases",
"StructureGroupName": "Glycosyltransferases",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "OWP_Organization",
"NameofStructureSystem": "Organization",
"StructureNodeID": "01-01-01-07-00",
"StructureGroupPath": "Roche Diagnostics Solution (RDS)->Customer Areas->Core lab->CustomBiotech and LifeScience",
"StructureGroupName": "CustomBiotech and LifeScience",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Product_Grouping",
"NameofStructureSystem": "Product Grouping",
"StructureNodeID": "02-0014",
"StructureGroupPath": "CustomBiotech->Enzymes",
"StructureGroupName": "Enzymes",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Product_Solutions",
"NameofStructureSystem": "Product Solutions",
"StructureNodeID": "520",
"StructureGroupPath": "CustomBiotech",
"StructureGroupName": "CustomBiotech",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Lab_Type",
"NameofStructureSystem": "Lab Types",
"StructureNodeID": "180-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Applications",
"NameofStructureSystem": "Applications",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "OWP_Techniques",
"NameofStructureSystem": "Techniques",
"StructureNodeID": "999-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Disease_Areas",
"NameofStructureSystem": "Disease Areas",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Pathogens",
"NameofStructureSystem": "Pathogens",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "OWP_Family",
"NameofStructureSystem": "Product Families",
"StructureNodeID": "999",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Health_Topics",
"NameofStructureSystem": "Health Topics",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
}
]
},
{
"ProductID": "3.2.17.2.3.3",
"BrandName": "UDP-Galactose animal-free",
"ProductNameAddition": "disodium salt, lyophilizate",
"ReferenceType": "Reagent",
"Classification": [
{
"IdentifierofStructureSystem": "Product_Grouping",
"NameofStructureSystem": "Product Grouping",
"StructureNodeID": "02-0052",
"StructureGroupPath": "CustomBiotech->In vitro Glycoengineering",
"StructureGroupName": "In vitro Glycoengineering",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "OWP_Product_Types",
"NameofStructureSystem": "Product Types",
"StructureNodeID": "70-001-00",
"StructureGroupPath": "Raw Materials->Activated sugars",
"StructureGroupName": "Activated sugars",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "OWP_Organization",
"NameofStructureSystem": "Organization",
"StructureNodeID": "01-01-01-07-00",
"StructureGroupPath": "Roche Diagnostics Solution (RDS)->Customer Areas->Core lab->CustomBiotech and LifeScience",
"StructureGroupName": "CustomBiotech and LifeScience",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Product_Solutions",
"NameofStructureSystem": "Product Solutions",
"StructureNodeID": "520",
"StructureGroupPath": "CustomBiotech",
"StructureGroupName": "CustomBiotech",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Lab_Type",
"NameofStructureSystem": "Lab Types",
"StructureNodeID": "180-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Applications",
"NameofStructureSystem": "Applications",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "OWP_Techniques",
"NameofStructureSystem": "Techniques",
"StructureNodeID": "999-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Disease_Areas",
"NameofStructureSystem": "Disease Areas",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Pathogens",
"NameofStructureSystem": "Pathogens",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "OWP_Family",
"NameofStructureSystem": "Product Families",
"StructureNodeID": "999",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Health_Topics",
"NameofStructureSystem": "Health Topics",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
}
]
},
{
"ProductID": "3.2.17.2.68.1",
"BrandName": "CMP-N-Acetylneuraminic Acid (CMP-NANA)",
"ProductNameAddition": "sodium salt, lyophilizate",
"ReferenceType": "Reagent",
"Classification": [
{
"IdentifierofStructureSystem": "Product_Grouping",
"NameofStructureSystem": "Product Grouping",
"StructureNodeID": "02-0052",
"StructureGroupPath": "CustomBiotech->In vitro Glycoengineering",
"StructureGroupName": "In vitro Glycoengineering",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "OWP_Product_Types",
"NameofStructureSystem": "Product Types",
"StructureNodeID": "70-001-00",
"StructureGroupPath": "Raw Materials->Activated sugars",
"StructureGroupName": "Activated sugars",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "OWP_Organization",
"NameofStructureSystem": "Organization",
"StructureNodeID": "01-01-01-07-00",
"StructureGroupPath": "Roche Diagnostics Solution (RDS)->Customer Areas->Core lab->CustomBiotech and LifeScience",
"StructureGroupName": "CustomBiotech and LifeScience",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Product_Solutions",
"NameofStructureSystem": "Product Solutions",
"StructureNodeID": "520",
"StructureGroupPath": "CustomBiotech",
"StructureGroupName": "CustomBiotech",
"StructureNodeStatus": "valid"
},
{
"IdentifierofStructureSystem": "Lab_Type",
"NameofStructureSystem": "Lab Types",
"StructureNodeID": "180-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Applications",
"NameofStructureSystem": "Applications",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "OWP_Techniques",
"NameofStructureSystem": "Techniques",
"StructureNodeID": "999-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Disease_Areas",
"NameofStructureSystem": "Disease Areas",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Pathogens",
"NameofStructureSystem": "Pathogens",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "OWP_Family",
"NameofStructureSystem": "Product Families",
"StructureNodeID": "999",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
},
{
"IdentifierofStructureSystem": "Health_Topics",
"NameofStructureSystem": "Health Topics",
"StructureNodeID": "99-00-00",
"StructureGroupPath": "",
"StructureGroupName": "",
"StructureNodeStatus": "invalid"
}
]
}
]
},
"ProductSpec": [
{
"ProductSpecVariant": {
"Chapters": [
{
"Language": "en",
"Value": "08 098 182 103: Unit of measure is \"gram\".
08 098 182 101: Unit of measure is \"piece\".",
"Country": "XG",
"Code": "CB - Order Information",
"Name": "CB - Order Information"
},
{
"Language": "en",
"Value": "β-1,4-Galactosyltransferase, rec. EQ can be used for
in vitro glycoengineering of glycoproteins,
e.g. therapeutic proteins, in drug development and manufacturing.",
"Country": "XG",
"Code": "Positioning",
"Name": "Positioning"
},
{
"Language": "en",
"Value": "No animal-derived material is added in fermentation, purification and final formulation of this enzyme.",
"Country": "XG",
"Code": "Quality Control",
"Name": "Quality Control"
},
{
"Language": "en",
"Value": "Benefits from
in vitro glycoengineering to modify glycosylation of therapeutic proteins:
- Time- and cost-saving generation of glycan variants to facilitate drug development.
- Optimized glycosylation without compromising other CQAs or product yield.
- Improved lot-to-lot consistency to reduce risk of product quality variation and resulting delays.
- Generation of glycoprofiles which may not otherwise be generated.
- Streamlined analytics in comparability studies.
",
"Country": "XG",
"Code": "Benefits",
"Name": "Benefits"
},
{
"Language": "en",
"Value": "β-1,4-Galactosyltransferase, rec. EQ is a highly active recombinant human glycosyltransferase, expressed in CHO cells.
To use
in vitro glycoengineering in drug development and manufacturing processes, enzymes should be of enhanced quality (EQ), compared to enzymes used in early R&D or analytical applications: Enzymes should be tested for host-cell impurities and relevant metal impurities and be available at least in gram amounts.
β-1,4-Galactosyltransferase, rec. EQ fulfills those criteria and can also be provided in GMP Grade upon request.",
"Country": "XG",
"Code": "Product Description",
"Name": "Product Description"
},
{
"Language": "en",
"Value": "Incubation of β-1,4-Galactosyltransferase and UDP-Galactose with a glycoprotein leads to increased galactosylation of the glycoprotein.",
"Country": "XG",
"Code": "Applications",
"Name": "Applications"
},
{
"Language": "en",
"Value": "
Appearance: Clear and colorless to slightly yellowish solution.
Specific activity: >12 U/mg
Protein (OD 280 nm) A280 = 0.984: 15 ± 1.5 mg/mL
Purity (HPLC): >90%
Bioburden: ≤100 CFU/mL
Endotoxin: ≤10 EU/mg
Host cell protein: ≤ 4000 ppm
Host cell DNA: ≤ 100 pg/mg
Heavy metal: (Cd, Co, V, Ni, Ag, Se); ≤ 10 ppm
Stability: At –15 to –25°C within specification range for 18 months (08 098 182 103) and 12 months (08 098 182 101).
",
"Country": "XG",
"Code": "Specification",
"Name": "Specification"
}
]
}
}
]
}