100 mM, pH 8.3

A solid start in mRNA synthesis

Ribonucleotides are the critical starting materials for the synthesis of mRNA by in vitro transcription.

Minimize risk and complications in the transition from development to industrial production of mRNA therapeutics or vaccines by relying on fit-for-purpose product quality from a high-volume NTP supplier.

  • Pandemic-ready supply
    Roche has invested in a brand-new manufacturing facility with customized automation technology designed exclusively for mRNA raw material requirements in consistent high quality and scale.
  • Sustainable and pure products
    Choose sustainability without compromise. Our nucleotides are produced through enzymatic catalysis, reducing impurities associated with chemical synthesis and ensuring high purity.
  • Innovation and expertise
    Leverage our extensive experience and expertise based on 30 years of nucleotide manufacturing at one of Europe's largest biotechnology centers in Penzberg, Germany.

Produced using validated manufacturing and cleaning processes up to the final filling step and released under stringent final QC checks. Know that you are getting consistent quality every time.

from the generation of the master cell bank to the final filling, noanimal-derived materials are used in the process. This greatly simplifies your risk analysis.

our proprietary E. coli strain eliminates the need for antibiotics during fermentation. Therefore, allergic reactions to antibiotics is not a factor in your overall risk analysis.

tested during final QC-release for the absence of impurities such as nucleases, host-cell DNA and protein, bioburden, heavy metals, or endotoxins. Work with an enzyme at peak performance that poses no risk to downstream processing.

We work with you to provide the necessary technical documents for your regulatory submissions.

Changing reagent quality between pre-clinical development and commercialization poses a risk. Secure your processes by using the best available quality from the start.

Ordering Information

Technical documents

for certificates, method sheets (instructions for use), safety data sheets and software downloads
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