{ "ProductData": { "ID": "3.6.5.5.4.6", "ProductType": "Others", "BrandName": "α-S-dCTP, Molecular Diagnostic Grade", "ProductNameAddition": "S-isomer, sodium salt, 100 mM", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": null, "DisclaimerGroup2": null, "RegulatoryDisclaimer3": null, "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "alpha-S-dCTP Molecular Diagnostic Grade" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Nucleotides", "NodeID": "02-0018" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "StructureNodeStatus": "valid", "NodeName": "Deoxyucleotides", "NodeID": "70-015-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Molecular Raw Materials", "NodeID": "02-0136" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "valid", "NodeName": "PCR/qPCR", "NodeID": "210-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "valid", "NodeName": "RT-PCR/qRT-PCR", "NodeID": "300-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "180-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "12207095103", "MaterialDescription": "Alpha-thio-d-CTP,Solution (Mol-DIA)", "RegisteredProductName": "alpha-S-dCTP, Molecular Diagnostic Grade", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "custom fill", "PackSizeDescPIM360": "Not Available", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"α-thio-d-CTP, Solution (Mol-DIA)\". Unit of measure is \"μmol\". " } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "Will be supplied as \"α-thio-d-CTP, Solution (Mol-DIA)\". Unit of measure is \"μmol\".", "Country": "XG", "Code": "CB - Order Information", "Name": "CB - Order Information" }, { "Language": "en", "Value": "Use α-S-dCTP in alternative amplification technologies such as Strand Displacement Amplification (SDA). In addition, these nucleotides can be used in applications, including amplification reactions when a higher resolution in capillary electrophoresis is desired. This product is the purified S-isomer, prepared using Roche's biocatalytical production process. Use of purified S-isomer eliminates the introduction of another isomer which does not participate in the amplification reaction as it is not a substrate for the polymerase.", "Country": "XG", "Code": "Applications", "Name": "Applications" }, { "Language": "en", "Value": "α-S-dCTP, Molecular Diagnostic Grade, is supplied in sealed and CO₂-proof bottles to ensure a stable pH during shipment on dry ice.", "Country": "XG", "Code": "Product Description", "Name": "Product Description" }, { "Language": "en", "Value": "Modified dCTP for Strand Displacement Amplification and other special applications.", "Country": "XG", "Code": "Positioning", "Name": "Positioning" }, { "Language": "en", "Value": "This α-S-dCTP is the purified S-isomer, not a diastereomeric mixture.", "Country": "XG", "Code": "Quality Control", "Name": "Quality Control" }, { "Language": "en", "Value": "Nomenclature: α-Thio-2'-deoxy-cytidine-5'-triphosphate
CAS Number: 6183-74-0
Formula: C₉H₁₆N₃O₁₂SP₃ x H₂O
Molecular weight: 483.2 D", "Country": "XG", "Code": "Properties", "Name": "Properties" }, { "Language": "en", "Value": "Appearance: Colorless solution
pH value: 8.1-8.5
α-S-dCTP (1 μmol ≙ 9.6 A₂₇₂ units): 90-100 mmol/L
α-S-dCTP, S-Isomer (HPLC): ≥98.0 area%
α-S-dCDP (HPLC): ≤1.5 area%
DNases/RNases: Negative
Nicking activity: Negative
A₂₅₀/A₂₆₀: 0.80-0.84
A₂₈₀/A₂₆₀: 0.95-1.00
A₂₉₀/A₂₆₀: 0.28-0.32
Stability: At -15 to -25°C within specification range for 12 months.", "Country": "XG", "Code": "Specification", "Name": "Specification" } ] } } ] }