For life science research only. Not for use in diagnostic procedures. Others alpha-2 3-Sialyltransferase rec. LSR α-2,3-Sialyltransferase, rec. 78 1403506419168 The sale of the Product does not exhaust or grant any rights in third party patents including patents of companies of the F. Hoffmann - La Roche AG group of companies, in particular, for the use of modified antibodies obtained by using the product. 3.1.1.2.13.1 human, expressed in HEK-293F, solution 07429916103 alpha-2,3-Sialyltransferase, rec. alpha-2,3-Sialyltransferase, rec. 07613336130766 Reagents, kits custom fill Not Available CustomBiotech product. Please contact your local representative. Unit of measure is "mg". For in vitro sialylation of all Galß1-4GlcNAc units on glycoproteins and complex molecules such as human monoclonal antibodies (MAB), use α-2,3-Sialyltransferase (ST3Gal-6) and CMP-N-Acetylneuraminic Acid (CMP-NANA). en α-2,3-Sialyltransferase, rec. can be used for in vitro glycoengineering of glycoproteins, e.g. therapeutic proteins. en Benefits of using in vitro glycoengineering to modify glycosylation of therapeutic proteins: Time- and cost-saving generation of glycan variants to facilitate drug development. Optimized glycosylation without compromising other CQAs or product yield. Improved lot-to-lot consistency to reduce risk of product quality variation and resulting delays. Generation of glycoprofiles which may not otherwise be generated. Streamlined analytics in comparability studies. en α-2,3-Sialyltansferase, rec. is a highly active recombinant human glycosyltransferase, expressed in HEK-293F. en Appearance: Clear, colorless to slightly colored solution. Composition: 50 mM MES, 200 mM NaCl, pH 6.4 ± 0.1 at +4°C Specific activity: ≥80 U/μg Protein A280nm ( 1 mg/mL) = 0.877: 5.5 ± 0.5 mg/mL Purity: ≥90% Bioburden: ≤100 CFU/mL (in evaluation) Endotoxin: ≤10 EU/mg (in evaluation) Stability: At -15 to -25°C within specification range for 12 months. en