Variation in glycosylation can impact the safety and efficacy profiles of a therapeutic product. With the right tools, glycosylation management can be uncoupled from the entangled processes of fermentation allowing you to pursue separate strategies to optimize glycosylation and yield, granting greater control over each.
Certain glycoforms can be enriched in downstream processing using discrete enzymatic reactions with clear kinetics and predictable outcomes. Resources are no longer wasted on uncertain tweaking of the bioprocess, leading to faster development as well as improved control of the manufacturing process.
