Hot start redefined
AptaTaq DNA polymerases are formulated in a glycerol-free solution at high concentrations, which guarantees their stability throughout the lyophilization process and subsequent storage. The AptaTaq polymerase family features an aptamer-oligonucleotide mixture with temperature-dependent tertiary structure that serves as a precise hot start switch.
Assays based on AptaTaq enzymes show a broad dynamic range. The specific and stable enzyme allows target detection down to very low copy numbers and shows no loss of activity after storage for 14 months at +2 to +8°C.