AptaTaq polymerases portfolio

Customized AptaTaq hot start solutions for your workflow

AptaTaq DNA polymerases are engineered in glycerol-free, high-concentration formulations to ensure maximum stability during lyophilization and long-term storage. The AptaTaq portfolio utilizes a specialized aptamer-oligonucleotide ligand with a temperature-dependent tertiary structure, functioning as a reversible and precise hot start molecular switch.

Assays utilizing AptaTaq enzymes deliver a broad dynamic range and exceptional sensitivity. This highly stable enzyme configuration enables reliable target detection at extremely low copy numbers, maintaining full enzymatic activity even after 14 months of storage at +2 to +8°C.

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The enzyme aptamer-oligonucleotide mixture is a reversible, temperature-dependent hot start system.

The aptamer acts as a molecular switch, changing its temperature-dependent tertiary structure. Dropping the temperature below +55°C shuts off the polymerase activity, while temperatures above +60°C fully activate the enzyme.