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Ig Fab Bio HT

Test kit for the Cedex Bio HT Analyzer

For use in quality control / manufacturing process only.

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Order information
Ig Fab Bio HT material number and pack size:
Material Number Pack Size
08881359001 200 tests
Unit of measure is "piece".
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Overview
Kit for determination of human immunoglobulin Fab fragments.
This product is intended for quantitative determination of human immunoglobulin Fab fragments in aqueous solutions using the Cedex Bio HT Analyzer.
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Application
In oncology, immunoglobulins (Ig) are used for therapeutic treatment. There is a need in the pharmaceutical development and manufacturing to determine the antibody concentrations. Complete IgG antibodies can be determined using the 'IgG Bio HT' test, detecting the highly conserved Fc part of the molecules. Nevertheless, a rising number of artificially designed Ig products consists of the target binding Fab part only, missing the Fc region. The 'Ig Fab Bio HT' test detects a constant region of the Kappa Light Chain in the Ig Fab fragment. Therefore, this test is suited also for the determination of truncated Ig fragments.
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Specification
Method: Immunoturbidimetric; 
Recovery: ± 15%