Framework IgG
lyophilizate
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Will be supplied as "Framework IgG *SQ". Unit of measure is "mg active ingredient".
Framework IgG material number and pack size: Material Number Pack Size 03369846103 custom fill -
Immunogen: PTH
Spleen donor: Mouse Balb/c
Antibody class: IgG1, kappa
Preparation: Framework IEP is lyophilized from a solution containing protein, potassium phosphate and NaCl. No further preservatives are added. - The monoclonal Framework IgG eliminates monomeric ("immuno-response") and highly specific interferences against the framework regions of the antibodies. Its interference eliminating strength is based on identical immuno-reactive conformational epitopes in the framework region of the test antibody.
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Molecular structure: IgG1, monomer
Remark: Cannot be used in test systems for determination of PTH.
Serum concentrations of CK-MM: ≤3 U/mL have shown neither influence on interference elimination properties nor on recovery of analyte. Appearance: White lyophilizate
Solubility: Clear, colorless to slightly opalescent solution in NaCl, 0.9% (c=10 mg/mL)
Purity (HPLC): ≥90% IgG of total protein
Functional activity (relative titer based on masterlot): ≥80%
Recommended working concentration: 20-5,000 μg/mL incubation buffer
pH 5.5 treatment (30 minutes): Corresponds to specification
Stability: At -15 to -25°C within specification range for 24 months. Avoid repeated freezing and thawing.