{ "ProductData": { "ID": "3.6.5.2.1.3", "ProductType": "Others", "BrandName": "ddTTP, Sequencing Grade", "ProductNameAddition": "sodium salt, 10 mM", "RegulatoryDisclaimer1": "For further processing only.", "DisclaimerGroup1": "", "RegulatoryDisclaimer2": null, "DisclaimerGroup2": null, "RegulatoryDisclaimer3": null, "SampleType": [ ], "LicenseDisclaimers": [ ], "RelatedLinks": "", "Clone": "", "ControlTissue": [ "" ], "ISOtypes": "", "Species": [ "" ], "StainLocalization": [ "" ], "ProductNameGlobal": "ddTTP Sequencing Grade" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxonomy": { "Product2TaxonomyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Nucleotides", "NodeID": "02-0018" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "StructureNodeStatus": "valid", "NodeName": "Dideoxynucleotides", "NodeID": "70-018-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "StructureNodeStatus": "valid", "NodeName": "Molecular Raw Materials", "NodeID": "02-0136" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "valid", "NodeName": "Labeling and Detection", "NodeID": "320-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "StructureNodeStatus": "valid", "NodeName": "RT-PCR/qRT-PCR", "NodeID": "300-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "StructureNodeStatus": "valid", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "180-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "StructureNodeStatus": "invalid", "NodeName": "", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "12158205103", "MaterialDescription": "Dideoxy-TTP,Na,Sequencing Grade,Solution", "RegisteredProductName": "ddTTP, Sequencing Grade", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "100 mL", "PackSizeDescPIM360": "1,000 μmol", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Dideoxy-TTP, Na, Sequencing Grade, Solution\". Unit of measure is \"μmol\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "ddTTP, Sequencing Grade, is supplied in sealed and CO₂-proof bottles to ensure a stable pH during shipment on dry ice. The pH is adjusted to match conditions for amplification.", "Country": "XG", "Code": "Product Description", "Name": "Product Description" }, { "Language": "en", "Value": "Will be supplied as \"Dideoxy-TTP, Na, Sequencing Grade, Solution\". Unit of measure is \"μmol\".", "Country": "XG", "Code": "CB - Order Information", "Name": "CB - Order Information" }, { "Language": "en", "Value": "ddTTP, Sequencing Grade, in dNTP mixes acts as chain terminator in sequencing and primer extension reactions. The high purity and carefully designed manufacturing process are ideally suited for the manufacturing of in vitro diagnostics.", "Country": "XG", "Code": "Applications", "Name": "Applications" }, { "Language": "en", "Value": "For consistent performance in sequencing applications and primer extension reactions, use dideoxyribonucleotides from the leading manufacturer of nucleotides.", "Country": "XG", "Code": "Positioning", "Name": "Positioning" }, { "Language": "en", "Value": "All dideoxynucleotides can be GMP manufactured upon request.", "Country": "XG", "Code": "Quality Control", "Name": "Quality Control" }, { "Language": "en", "Value": "Appearance: Clear, colorless solution
pH value: 8.1-8.5
ddTTP (1 μmol ≙ 8.4 A₂₆₀ units, pH 7.0): 10.0-11.0 mmol/L
ddTTP (HPLC): ≥98 area%
ddTDP (HPLC): ≤1.5 area%
DNases/RNases: Negative
Nicking activity: Negative
A₂₅₀/A₂₆₀: 0.60±0.02
A₂₈₀/A₂₆₀: 0.83±0.03
A₂₉₀/A₂₆₀: 0.31±0.02
Stability: At -15 to -25°C within specification range for 24 months.", "Country": "XG", "Code": "Specification", "Name": "Specification" }, { "Language": "en", "Value": "Nomenclature: 2',3'-Dideoxy-thymidine-5'-triphosphate
CAS Number: 128524-26-5
Formula: C₁₀H₁₇N₂O₁₃P₃
Molecular weight: 466.2 D", "Country": "XG", "Code": "Properties", "Name": "Properties" } ] } } ] }