{ "ProductData": { "RelatedLinks": "", "RegulatoryDisclaimer1": "For further processing only.", "RegulatoryDisclaimer2": "", "StainLocalization": [ "" ], "ProductType": "Others", "DisclaimerGroup2": null, "ProductNameGlobal": "ddTTP Sequencing Grade", "DisclaimerGroup1": "Non-IVD", "ControlTissue": [ "" ], "BrandName": "ddTTP, Sequencing Grade", "LicenseDisclaimers": [ ], "Isotypes": "", "RegulatoryDisclaimer3": "", "ID": "3.6.5.2.1.3", "ProductNameAddition": "sodium salt, 10 mM", "Species": [ "" ], "Clone": "" }, "ProductImageDetails": { "ImagePath": "https://pim-media.roche.com/Images/CB_IMAGE.png", "ImageType": "Image main" }, "Product2Taxomony": { "Product2TaxomonyReferences": [ { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Nucleotides", "NodeID": "02-0018" }, { "StructureSystemIdentifier": "OWP_Product_Types", "StructureSystemName": "Product Types", "NodeName": "Dideoxynucleotides", "NodeID": "70-018-00" }, { "StructureSystemIdentifier": "OWP_Organization", "StructureSystemName": "Organization", "NodeName": "CustomBiotech and LifeScience", "NodeID": "01-01-01-07-00" }, { "StructureSystemIdentifier": "Product_Grouping", "StructureSystemName": "Product Grouping", "NodeName": "Molecular Raw Materials", "NodeID": "02-0136" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeName": "Labeling and Detection", "NodeID": "320-00" }, { "StructureSystemIdentifier": "OWP_Techniques", "StructureSystemName": "Techniques", "NodeName": "RT-PCR/qRT-PCR", "NodeID": "300-00" }, { "StructureSystemIdentifier": "Product_Solutions", "StructureSystemName": "Product Solutions", "NodeName": "CustomBiotech", "NodeID": "520" }, { "StructureSystemIdentifier": "Lab_Type", "StructureSystemName": "Lab Types", "NodeName": "Manufacturing", "NodeID": "180-00" }, { "StructureSystemIdentifier": "Applications", "StructureSystemName": "Applications", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Disease_Areas", "StructureSystemName": "Disease Areas", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "Pathogens", "StructureSystemName": "Pathogens", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" }, { "StructureSystemIdentifier": "OWP_Family", "StructureSystemName": "Product Families", "NodeName": "NOT APPLICABLE", "NodeID": "999" }, { "StructureSystemIdentifier": "Health_Topics", "StructureSystemName": "Health Topics", "NodeName": "NOT APPLICABLE", "NodeID": "99-00-00" } ] }, "Product2Materials": { "P2MaterialReferences": [ { "MaterialNum": "12158205103", "MaterialDescription": "Dideoxy-TTP,Na,Sequencing Grade,Solution", "RegisteredProductName": "ddTTP, Sequencing Grade", "GTIN": "", "ProductCategoryText": "Reagents, kits", "OldMaterialNumber": "", "PackSizePIM360": "100 mL", "PackSizeDescPIM360": "1,000 μmol", "MaterialAnnotation": "CustomBiotech product. Please contact your local representative.", "ReadyForUse": "", "OrderInformation": "Will be supplied as \"Dideoxy-TTP, Na, Sequencing Grade, Solution\". Unit of measure is \"μmol\"." } ] }, "Product2Products": { "Product2ProductReference": [ ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "ddTTP, Sequencing Grade, is supplied in sealed and CO2-proof bottles to ensure a stable pH during shipment on dry ice. The pH is adjusted to match conditions for amplification.", "Name": "Product Description" }, { "Language": "en", "Value": "Will be supplied as \"Dideoxy-TTP, Na, Sequencing Grade, Solution\". Unit of measure is \"μmol\".", "Name": "CB - Order Information" }, { "Language": "en", "Value": "ddTTP, Sequencing Grade, in dNTP mixes acts as chain terminator in sequencing and primer extension reactions. The high purity and carefully designed manufacturing process are ideally suited for the manufacturing of in vitro diagnostics.", "Name": "Applications" }, { "Language": "en", "Value": "For consistent performance in sequencing applications and primer extension reactions, use dideoxyribonucleotides from the leading manufacturer of nucleotides.", "Name": "Positioning" }, { "Language": "en", "Value": "All dideoxynucleotides can be GMP manufactured upon request.", "Name": "Quality Control" }, { "Language": "en", "Value": "Appearance: Clear, colorless solution
pH value: 8.1-8.5
ddTTP (1 μmol ≙ 8.4 A260 units, pH 7.0): 10.0-11.0 mmol/L
ddTTP (HPLC): ≥98 area%
ddTDP (HPLC): ≤1.5 area%
DNases/RNases: Negative
Nicking activity: Negative
A250/A260: 0.60±0.02
A280/A260: 0.83±0.03
A290/A260: 0.31±0.02
Stability: At -15 to -25°C within specification range for 24 months.", "Name": "Specification" }, { "Language": "en", "Value": "Nomenclature: 2',3'-Dideoxy-thymidine-5'-triphosphate
CAS Number: 128524-26-5
Formula: C10H17N2O13P3
Molecular weight: 466.2 D", "Name": "Properties" } ] } } ] }

ddTTP, Sequencing Grade

sodium salt, 10 mM

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