The most important cations for the living cells in the cell culture and microbial fermentation are sodium (Na+) and potassium (K+). A common method for determination of these ions is the use of ion-selective electrodes (ISE). However, ISE are susceptible to various interferences and require frequent maintenance and continuous recalibration in short intervals.
Therefore, the Cedex Bio and Bio HT Analyzers are now using the proven format of enzyme-based assays with photometric detection which also work for Na+ and K+, making the ISE module obsolete.
Discover more about the replacement of the Cedex ISE module in this brochure