Molecular Testing

Choose the Complete Solution

  • A smooth workflow from sample preparation to detection begins with meticulous assay design, high-quality reagents, and a flawless kit production process. As diagnostics manufacturer and the leading raw materials provider for molecular diagnostics assays we completely understand the needs of diagnostic companies.
  • GMP production ensures extensive documentation for submission to regulatory authorities, highest possible quality, performance, reproducibility, and supply security.
  • We provide customizable master mixes, oligonucleotides, pre-filled microplates, and kits.


Nucleic Acid Isolation and Purification

Custom Biotech recombinant Proteinase K and DNase I are rigorously tested to exclude the introduction of contaminants such as RNase activity. Custom Biotech also offers custom solutions for manual preparation, for automated sample preparation, and for high-throughput real-time PCR.


Amplification of DNA Targets by PCR

In the development of diagnostic assays, the choice of amplification polymerase is key to success. Custom Biotech offers a broad portfolio of nucleic acid amplification enzymes. Taq DNA Polymerase is by far the most versatile and robust polymerase for PCR. 


Amplification of RNA Targets by PCR

Reverse Transcriptases are fundamental for successful RT-PCR and other amplification technologies. Roche offers AMV RT and M-MLV RT, both produced under GMP. As with all other GMP products in our portfolio, the focus is on extensive characterization and performance testing for high lot-to-lot consistency. For one-step RT-PCR with two-step performance, AllStart RNA Master is the perfect choice.


Amplification Performance Enhancement

Optimizing an assay to perfection is no simple feat. Custom Biotech offers a toolbox to achieve highest specificity and sensitivity, from inhibiting RNases and eliminating carryover contamination, to recombinant T4 Gene 32 Protein, a powerful tool to increase test performance.


Alternative Amplification Methods

Our portfolio also provides resources for other amplification technologies, such as Nucleic Acid Sequence-Based Amplification (NASBA) and Transcription Mediated Amplification (TMA).


Additional Applications

Detect amplification products with our hapten and fluorescent labels and antibody conjugates. Our extensive experience with modified-nucleotide chemistry and conjugate preparation makes us an ideal supplier for all your labeling and detection needs.